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Purpose <p>To assess non-medical opioid use (NMOU) risk frequency in outpatients with cancer, compare at-risk vs. non-risk patients, and evaluate the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) against its shortened version (SOAPP-SF).</p> Methods <p>/patients.</p> <p>This cross-sectional study was conducted in a tertiary hospital’s palliative care clinic. Adult patients with advanced cancer and cancer pain using or initiating prescribed opioids were included. Patients self-completed the SOAPP-R and SOAPP-SF during consultations. Additional data were gathered from medical records.</p> Results <p>A total of 47 patients completed SOAPP-R and SOAPP-SF to assess NMOU risk, with 28% (<i>n</i> = 13) classified as high-risk by both. High-risk patients were younger (<i>p</i> = 0.003), received higher opioid doses (<i>p</i> = 0.026), used more substances (<i>p</i> = 0.018), and were more frequently employed (<i>p</i> = 0.001). SOAPP-SF showed 0.85 specificity, 0.6 sensitivity, 0.85 negative predictive value, and 0.6 positive predictive value compared to SOAPP-R. Both tests agreed on 61.5% of high-risk and 85% of low-risk cases.</p> Conclusions <p>Among outpatients with advanced cancer, 28% had high NMOU risk, which was associated with younger age, higher opioid doses, greater substance use, and higher employment rates. SOAPP-SF retained most of the predictive power of the SOAPP-R.</p>

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Frequency and predictors of risk of non-medical opioid use among patients with cancer in a specialized outpatient palliative care clinic

  • 期刊论文

  • 发表日期：

    2025年4月19日

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  • Juan Luis Torres-Tenor,
  • Eduardo Bruera,
  • Inés Sánchez-Mañas,
  • Teresa Pérez-Manrique,
  • Aránzazu Castellano-Candalija,
  • Alberto Alonso-Babarro

摘要

Purpose

To assess non-medical opioid use (NMOU) risk frequency in outpatients with cancer, compare at-risk vs. non-risk patients, and evaluate the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) against its shortened version (SOAPP-SF).

Methods

/patients.

This cross-sectional study was conducted in a tertiary hospital’s palliative care clinic. Adult patients with advanced cancer and cancer pain using or initiating prescribed opioids were included. Patients self-completed the SOAPP-R and SOAPP-SF during consultations. Additional data were gathered from medical records.

Results

A total of 47 patients completed SOAPP-R and SOAPP-SF to assess NMOU risk, with 28% (n = 13) classified as high-risk by both. High-risk patients were younger (p = 0.003), received higher opioid doses (p = 0.026), used more substances (p = 0.018), and were more frequently employed (p = 0.001). SOAPP-SF showed 0.85 specificity, 0.6 sensitivity, 0.85 negative predictive value, and 0.6 positive predictive value compared to SOAPP-R. Both tests agreed on 61.5% of high-risk and 85% of low-risk cases.

Conclusions

Among outpatients with advanced cancer, 28% had high NMOU risk, which was associated with younger age, higher opioid doses, greater substance use, and higher employment rates. SOAPP-SF retained most of the predictive power of the SOAPP-R.