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<p>Sphenoid sinus disease is a rare cause of abducens nerve palsy leading to lateral gaze restriction. Isolated abducens nerve palsy is a diagnosis of exclusion and pathology along course of abducens nerve from pons to lateral rectus muscle can cause lateral rectus palsy. Several etiological conditions can be responsible for the clinical condition- infective, inflammatory, neoplastic, fibroosseous lesions, encephalocele, vascular aneurysm and traumatic injury. Non specific symptoms of isolated sphenoid sinus disease usually cause delay in diagnosis and further leading to complications pertaining to adjacent structures. Sphenoid sinus is in close proximity to cranial nerves (optic, occulomotor, trochlear, ophthalamic and maxillary division of trigeminal, abducens nerve), internal carotid artery and cavernous sinus and involvement can lead to devastating complications. Early recognition and management is of paramount importance in isolated sphenoid sinus disease to prevent progression of disease. Prompt endoscopic sphenoid sinusotomy is management of choice and timely intervention prevents irreversible neurological deficit. Visual prognosis in isolated sphenoid sinus disease due to benign infective and inflammatory pathology is favourable when managed effectively.</p>

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Case Series: Management of Isolated Abducens Nerve Palsy Secondary to Sphenoid Sinus Disease

  • 期刊论文

  • 发表日期：

    2026年4月7日

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  • Tashi Negi,
  • Vaibhav Saini,
  • Vikasdeep Gupta,
  • Nikhil Rajan,
  • Ankur Mohan,
  • Sanjay Kumar,
  • Ayushi Sharma,
  • Ishita Dhamija

摘要

Sphenoid sinus disease is a rare cause of abducens nerve palsy leading to lateral gaze restriction. Isolated abducens nerve palsy is a diagnosis of exclusion and pathology along course of abducens nerve from pons to lateral rectus muscle can cause lateral rectus palsy. Several etiological conditions can be responsible for the clinical condition- infective, inflammatory, neoplastic, fibroosseous lesions, encephalocele, vascular aneurysm and traumatic injury. Non specific symptoms of isolated sphenoid sinus disease usually cause delay in diagnosis and further leading to complications pertaining to adjacent structures. Sphenoid sinus is in close proximity to cranial nerves (optic, occulomotor, trochlear, ophthalamic and maxillary division of trigeminal, abducens nerve), internal carotid artery and cavernous sinus and involvement can lead to devastating complications. Early recognition and management is of paramount importance in isolated sphenoid sinus disease to prevent progression of disease. Prompt endoscopic sphenoid sinusotomy is management of choice and timely intervention prevents irreversible neurological deficit. Visual prognosis in isolated sphenoid sinus disease due to benign infective and inflammatory pathology is favourable when managed effectively.