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<p>Lesions over the nasal region are common, yet certain pathologies are exceedingly rare, often posing diagnostic challenges due to their unusual location and non-specific presentation. We present a series of three uncommon nasal lesions—chondroid syringoma, dermatofibrosarcoma protuberans (DFSP), and pilonidal sinus—highlighting their clinical features, diagnostic approach, and management strategies. Patient 1 involved a 33-year-old male with a slow-growing, painless mass at the nasal root diagnosed as chondroid syringoma on histopathology following wide local excision. Patient 2 was a 66-year-old female with a long-standing glabellar swelling, rapidly enlarging over six months, confirmed as DFSP after excision and histological evaluation. Patient 3 featured an 8-year-old boy with a congenital nasal bridge opening discharging hair, later diagnosed as pilonidal sinus; complete excision with bone surface smoothing was performed to prevent recurrence. In all cases, imaging was utilised to exclude deeper or intracranial extension, and complete surgical excision with primary closure achieved favourable cosmetic and functional outcomes. Rare nasal lesions such as chondroid syringoma, DFSP, and pilonidal sinus, though uncommon, should be considered in the differential diagnosis of midline nasal swellings. A thorough clinical examination supplemented by appropriate imaging is essential for accurate diagnosis and surgical planning. Complete excision with negative margins remains the mainstay of treatment, offering excellent prognosis when coupled with careful closure techniques to preserve cosmesis and prevent recurrence.</p>

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Rare Lesions at the Root of Nose: A Case Series of Three Unusual Presentations

  • 期刊论文

  • 发表日期：

    2026年3月30日

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  • Paramita Debnath,
  • Misbahul Haque,
  • Prakriti Samaddar

摘要

Lesions over the nasal region are common, yet certain pathologies are exceedingly rare, often posing diagnostic challenges due to their unusual location and non-specific presentation. We present a series of three uncommon nasal lesions—chondroid syringoma, dermatofibrosarcoma protuberans (DFSP), and pilonidal sinus—highlighting their clinical features, diagnostic approach, and management strategies. Patient 1 involved a 33-year-old male with a slow-growing, painless mass at the nasal root diagnosed as chondroid syringoma on histopathology following wide local excision. Patient 2 was a 66-year-old female with a long-standing glabellar swelling, rapidly enlarging over six months, confirmed as DFSP after excision and histological evaluation. Patient 3 featured an 8-year-old boy with a congenital nasal bridge opening discharging hair, later diagnosed as pilonidal sinus; complete excision with bone surface smoothing was performed to prevent recurrence. In all cases, imaging was utilised to exclude deeper or intracranial extension, and complete surgical excision with primary closure achieved favourable cosmetic and functional outcomes. Rare nasal lesions such as chondroid syringoma, DFSP, and pilonidal sinus, though uncommon, should be considered in the differential diagnosis of midline nasal swellings. A thorough clinical examination supplemented by appropriate imaging is essential for accurate diagnosis and surgical planning. Complete excision with negative margins remains the mainstay of treatment, offering excellent prognosis when coupled with careful closure techniques to preserve cosmesis and prevent recurrence.