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Introduction <p>Mucoepidermoid carcinomas (MECs) are low-grade tumors that occur in the salivary glands and to a lesser extent in larynx, gastrointestinal tract, and many other organs. They are rare to occur as a primary thyroid tumor.</p> Case Report <p>We present a 36-year-old male presented with diffuse enlargement of the thyroid gland on CT scan with homogeneous reduced attenuation and enlarged lymph nodes. A needle biopsy showed inflammatory fibrosing lesion and the possibility of unsampled malignancy was raised. A total thyroidectomy with sampling of mediastinal lymph nodes was performed and histology showed MEC in a background of chronic thyroiditis. A total of six lymph nodes were involved by tumor deposits.</p> Conclusion <p>Primary MEC of the thyroid usually follows an indolent course, however about fifth of the patients show an aggressive behavior. We present an example of thyroid MEC with lymph node metastases at presentation. Currently, there is no consensus on their optimal management plan, and they should be managed in a multidisciplinary fashion.</p>

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Primary Mucoepidermoid Carcinoma of the Thyroid with Lymph Node Metastases: A Case Report of a Rare Entity and Review of Literature

  • 期刊论文

  • 发表日期：

    2026年3月10日

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  • Asem Shalaby,
  • Al-Thuraiya Al-Senani,
  • Hajar Al Shukaili,
  • Eiman Al-Ajmi,
  • Asim Qureshi,
  • Suad Al Jahdhami,
  • Yahya Al Baddai

摘要

Introduction

Mucoepidermoid carcinomas (MECs) are low-grade tumors that occur in the salivary glands and to a lesser extent in larynx, gastrointestinal tract, and many other organs. They are rare to occur as a primary thyroid tumor.

Case Report

We present a 36-year-old male presented with diffuse enlargement of the thyroid gland on CT scan with homogeneous reduced attenuation and enlarged lymph nodes. A needle biopsy showed inflammatory fibrosing lesion and the possibility of unsampled malignancy was raised. A total thyroidectomy with sampling of mediastinal lymph nodes was performed and histology showed MEC in a background of chronic thyroiditis. A total of six lymph nodes were involved by tumor deposits.

Conclusion

Primary MEC of the thyroid usually follows an indolent course, however about fifth of the patients show an aggressive behavior. We present an example of thyroid MEC with lymph node metastases at presentation. Currently, there is no consensus on their optimal management plan, and they should be managed in a multidisciplinary fashion.