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<p>Fine Needle Aspiration Cytology (FNAC) is an accurate, safe, minimally invasive, outpatient procedure and cost-effective diagnostic technique. It is widely accepted as one of the preferred first-line investigations for evaluating neck swellings. This prospective study was done over the period of 12 months at tertiary care government medical college, Department of ENT and Head and Neck Surgery in southern India with 50 clinically palpable neck swellings patients were taken as a sample. statistical analysis included are sensitivity, specificity, positive predictive value, negative predictive value and accuracy. On FNAC examination, 41 cases were benign, and 9 cases were malignant or suspicious. On HPE, 43 were benign while 7 cases were malignant from suspicious and malignant cases, leaving 4 discordant cases. Sensitivity is 77.8%, Specificity is 100%, PPV is 100%, NPV is 95.3%, and accuracy is 96%. FNAC is a safe, quick, and affordable outpatient procedure with high accuracy and minimal discomfort, making it ideal for diagnosing neck swellings in all age groups. Despite its advantages, FNAC should complement, not replace, to histopathology to ensure accurate diagnosis and better patient care.</p>

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A Clinical Study on Correlation of Fine Needle Aspiration Cytology with Histopathological Examination in Diagnosis of Neck Swelling in a Tertiary Care Hospital

  • 期刊论文

  • 发表日期：

    2026年1月30日

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  • Ilakkiya Durairaj,
  • Sankar Gopi Chellappa,
  • Naadia Rengarajan

摘要

Fine Needle Aspiration Cytology (FNAC) is an accurate, safe, minimally invasive, outpatient procedure and cost-effective diagnostic technique. It is widely accepted as one of the preferred first-line investigations for evaluating neck swellings. This prospective study was done over the period of 12 months at tertiary care government medical college, Department of ENT and Head and Neck Surgery in southern India with 50 clinically palpable neck swellings patients were taken as a sample. statistical analysis included are sensitivity, specificity, positive predictive value, negative predictive value and accuracy. On FNAC examination, 41 cases were benign, and 9 cases were malignant or suspicious. On HPE, 43 were benign while 7 cases were malignant from suspicious and malignant cases, leaving 4 discordant cases. Sensitivity is 77.8%, Specificity is 100%, PPV is 100%, NPV is 95.3%, and accuracy is 96%. FNAC is a safe, quick, and affordable outpatient procedure with high accuracy and minimal discomfort, making it ideal for diagnosing neck swellings in all age groups. Despite its advantages, FNAC should complement, not replace, to histopathology to ensure accurate diagnosis and better patient care.