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<p>Central giant cell granuloma (CGCG) is a benign but locally aggressive lesion that commonly affects the jawbones. This case report discusses the clinical presentation, diagnosis, and management of CGCG in a 37-year-old female patient who presented with swelling and pain on the lower right side of her face. Initial investigations included imaging studies and histopathological analysis, which confirmed the diagnosis of CGCG. Considering patient’s young age and the lesion’s impact on her quality of life, conservative treatment was prioritized. Intralesional steroid injections consisting of 5 mL of 10&#xa0;mg/mL triamcinolone (Kenacort-A) mixed with 2% Lidocaine were administered twice weekly for three months. However, due to insufficient response, a segmental resection of the mandible was performed, followed by reconstruction using a vascularized fibula graft. This approach not only restored the structural integrity of the mandible but also enhanced the functional and aesthetic outcomes. This case underscores the importance of a multidisciplinary approach in treating CGCG, with careful consideration of individual patient factors to optimize outcomes.</p>

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Strategies for Treating Central Giant Cell Granuloma in the Mandible: From Diagnosis to Follow-Up

  • 期刊论文

  • 发表日期：

    2025年10月14日

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  • Kshitij Bang,
  • Rutuja Deshmukh,
  • Vrinda Kolte,
  • Ramakrishna Shenoi

摘要

Central giant cell granuloma (CGCG) is a benign but locally aggressive lesion that commonly affects the jawbones. This case report discusses the clinical presentation, diagnosis, and management of CGCG in a 37-year-old female patient who presented with swelling and pain on the lower right side of her face. Initial investigations included imaging studies and histopathological analysis, which confirmed the diagnosis of CGCG. Considering patient’s young age and the lesion’s impact on her quality of life, conservative treatment was prioritized. Intralesional steroid injections consisting of 5 mL of 10 mg/mL triamcinolone (Kenacort-A) mixed with 2% Lidocaine were administered twice weekly for three months. However, due to insufficient response, a segmental resection of the mandible was performed, followed by reconstruction using a vascularized fibula graft. This approach not only restored the structural integrity of the mandible but also enhanced the functional and aesthetic outcomes. This case underscores the importance of a multidisciplinary approach in treating CGCG, with careful consideration of individual patient factors to optimize outcomes.