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Purpose <p>Coronary artery bypass grafting (CABG) has set the benchmark for managing multivessel coronary artery disease (CAD), providing superior mid-term outcomes. However, limited regional data, particularly from South India, exist on mid-term post-CABG outcomes. This study attempts to evaluate survival, major adverse cardiac and cerebrovascular events (MACCE), and freedom from repeat revascularisation over a 5-year follow-up period in patients undergoing CABG at a tertiary referral center.</p> Methods <p>A retrospective cohort study was conducted on 1634 patients who underwent isolated CABG from January 2003 to December 2007. Data were collected from institutional records, and follow-up information was obtained via outpatient visits, phone calls, and mail. Overall survival and MACCE free survival were assessed using Kaplan–Meier curves. Statistical significance was determined using log-rank tests (p &lt; 0.05).</p> Results <p>Follow up was done for 5&#xa0;years, after surgery. 11.32% of patients were lost to follow up at 5&#xa0;years. The cumulative MACCE rate at 5&#xa0;years was 5.87%. Overall survival at 5&#xa0;years was 85.74%. Repeat revascularization was done for 12 patients. Symptom free survival dropped to 75.56% at 5&#xa0;years (Fig.&#xa0;<InternalRef RefID="Fig1">1</InternalRef>).</p> Conclusions <p>CABG provides excellent mid-term survival, MACCE-free outcomes and freedom from repeat revascularisation in patients with multivessel CAD, at 5&#xa0;years follow up. This study contributes valuable insights into CABG outcomes in the Indian population and underscores the importance of regional data for optimizing care strategies.</p> Graphical abstract <p></p>

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Outcomes of coronary artery bypass grafting: insights from a single centre in South India

  • 期刊论文

  • 发表日期：

    2026年4月14日

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  • Sameer Mohammed,
  • Bineesh Kundoly Radhakrishnan,
  • Remya Sudevan,
  • Varghese Thomas Panicker,
  • Vivek Velayudhan Pillai,
  • Jayakumar Karunakaran

摘要

Purpose

Coronary artery bypass grafting (CABG) has set the benchmark for managing multivessel coronary artery disease (CAD), providing superior mid-term outcomes. However, limited regional data, particularly from South India, exist on mid-term post-CABG outcomes. This study attempts to evaluate survival, major adverse cardiac and cerebrovascular events (MACCE), and freedom from repeat revascularisation over a 5-year follow-up period in patients undergoing CABG at a tertiary referral center.

Methods

A retrospective cohort study was conducted on 1634 patients who underwent isolated CABG from January 2003 to December 2007. Data were collected from institutional records, and follow-up information was obtained via outpatient visits, phone calls, and mail. Overall survival and MACCE free survival were assessed using Kaplan–Meier curves. Statistical significance was determined using log-rank tests (p < 0.05).

Results

Follow up was done for 5 years, after surgery. 11.32% of patients were lost to follow up at 5 years. The cumulative MACCE rate at 5 years was 5.87%. Overall survival at 5 years was 85.74%. Repeat revascularization was done for 12 patients. Symptom free survival dropped to 75.56% at 5 years (Fig. 1).

Conclusions

CABG provides excellent mid-term survival, MACCE-free outcomes and freedom from repeat revascularisation in patients with multivessel CAD, at 5 years follow up. This study contributes valuable insights into CABG outcomes in the Indian population and underscores the importance of regional data for optimizing care strategies.

Graphical abstract