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Background <p>This study was aimed at reporting the clinical characteristics and perioperative surgical outcomes of mediastinal mature teratoma managed in a single surgical unit.</p> Methods <p>This is a retrospective analysis of 35 cases of mediastinal mature teratoma cases managed in a tertiary level thoracic surgery center over 10&#xa0;years. A comprehensive analysis of perioperative surgical outcomes including complications was performed.</p> Results <p>Males (<i>n</i> = 22, 62.8%) were predominant in the study group. Mean age of the cohort was 31.2 ± 13.3&#xa0;years. The diagnosis was unruptured mature teratoma in 17(48.6%), ruptured mature teratoma in 8 (22.8%) and mature cystic teratoma in 10 (28.6%) patients. The mean duration from symptoms was 5.5&#xa0;months (range: 1 – 84&#xa0;months). Open surgery was done in 22 patients (62.8%) followed by video-assisted thoracoscopic surgery in 4 (11.4%) and robotic surgery in 9 patients (25.7%). Conversion from minimal access surgery to open surgery was in 2 patients (5.7%). The mean duration of intercostal chest drainage (ICD) was 6.3 ± 1.3&#xa0;days, and mean hospital stay averaged 5.8 ± 2.7&#xa0;days. Most common postoperative complication was prolonged post-operative air leak (&gt; 7&#xa0;days) in 5 patients (14.3%). The peri-operative mortality was in 1 (2.8%) patient. Ruptured teratoma was a strong predictor of postoperative complications (<i>p</i> = 0.008).</p> Conclusion <p>Complete surgical resection is primary and effective treatment modality for mediastinal mature teratoma. A tailored approach is needed, considering the factors like tumor size, location, and relation with surrounding structures.</p> Graphical abstract <p></p>

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Surgical outcomes in mediastinal mature teratoma

  • 期刊论文

  • 发表日期：

    2025年1月18日

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  • Mohan Venkatesh Pulle,
  • Anmol Bhan,
  • Sukhram Bishnoi,
  • Belal Bin Asaf,
  • Harsh Vardhan Puri,
  • Sumit Bangeria,
  • Manan Bharatkumar Parikh,
  • Arvind Kumar

摘要

Background

This study was aimed at reporting the clinical characteristics and perioperative surgical outcomes of mediastinal mature teratoma managed in a single surgical unit.

Methods

This is a retrospective analysis of 35 cases of mediastinal mature teratoma cases managed in a tertiary level thoracic surgery center over 10 years. A comprehensive analysis of perioperative surgical outcomes including complications was performed.

Results

Males (n = 22, 62.8%) were predominant in the study group. Mean age of the cohort was 31.2 ± 13.3 years. The diagnosis was unruptured mature teratoma in 17(48.6%), ruptured mature teratoma in 8 (22.8%) and mature cystic teratoma in 10 (28.6%) patients. The mean duration from symptoms was 5.5 months (range: 1 – 84 months). Open surgery was done in 22 patients (62.8%) followed by video-assisted thoracoscopic surgery in 4 (11.4%) and robotic surgery in 9 patients (25.7%). Conversion from minimal access surgery to open surgery was in 2 patients (5.7%). The mean duration of intercostal chest drainage (ICD) was 6.3 ± 1.3 days, and mean hospital stay averaged 5.8 ± 2.7 days. Most common postoperative complication was prolonged post-operative air leak (> 7 days) in 5 patients (14.3%). The peri-operative mortality was in 1 (2.8%) patient. Ruptured teratoma was a strong predictor of postoperative complications (p = 0.008).

Conclusion

Complete surgical resection is primary and effective treatment modality for mediastinal mature teratoma. A tailored approach is needed, considering the factors like tumor size, location, and relation with surrounding structures.

Graphical abstract