<p>Brain tumors are considered one of the most dangerous and deadly diseases that affect humans around the globe. It is vital, yet hard to detect brain tumors at their early stages since they are small in size and have minor impacts on human activity. In this article, three small-sized antennas are designed and verified to detect very small-sized brain tumors ranging from 1 to 20 mm. The proposed antenna’s shape is designed similarly to the satellite-dish shape. The sizes of the proposed three antennas are (40 × 30 × 0.4), (30 × 30 × 0.6) and (30 × 30 × 0.7) mm³ respectively. A comprehensive analysis of the proposed antennas’ performance has been carried out. The analysis includes an investigation of the effect of changing the location and size of the tumor and the location of the antenna feedline on the antenna’s operating frequency and bandwidth. The gain, SAR, directivity, radiation pattern, VSWR and return losses are calculated. The sensitivity of the antenna to changes in the location, size and distance of the tumor within the skull, as well as the effect of dielectric properties is evaluated. Further, the efficiency of determining the type of tumor, whether it is benign or malignant, is studied. The validation results revealed that the proposed antennas can detect a tumor size of 1–20 mm with a good degree of discrimination between benign and malignant tumors. Comparison results show that the proposed antennas outperform the previous study in terms of antenna gain, directivity, and the ability of tumor detection and recognition.</p>