<p>A high-resolution record of foraminiferal stable isotopes at ODP hole 728A in the western Arabian Sea is used to estimate the hydrographic changes in surface and intermediate water, with a particular emphasis on understanding the role of southern sourced Antarctic Intermediate Water (AAIW) and North Atlantic climate in this region. Primarily, the planktic and benthic foraminiferal oxygen isotope records (δ¹⁸O_P and δ¹⁸O_B) appear to reflect large-scale glacial/interglacial variations of surface and intermediate water temperature. The significant decline in the δ¹⁸O_P value and prominently higher difference in δ¹⁸O_B–P during interstadial MIS5e suggest higher SST and a significant rise in upwelling-induced surface water productivity due to strong southwest (SW) monsoon. A large negative excursion of δ¹³C_B–P during interstadial MIS5e further supports the increased surface water productivity. The oxygen isotope data (δ¹⁸O_P) also demonstrates a millennial-scale in-phase relationship of western Arabian Sea SST with the Greenland temperature, suggesting an effective teleconnection with North Atlantic climate change. During North Atlantic cold Heinrich episodes, the increased northward advection of southern sourced glacial AAIW reached up to the northwestern part of the Arabian Sea, largely replacing the outflow of Red Sea Water (RSW) and Persian Gulf Water (PGW). An antiphase relationship of the δ¹³C_B record of the North Atlantic with those of the western Arabian Sea and southwest Pacific during cold Heinrich events demonstrates synchronicity in accelerated northward expansions of glacial AAIW and reduced Atlantic Meridional Overturning Circulation (AMOC), explaining the close linkage between inter-hemispheric millennial-scale climatic change.</p>