Scholarlink

Background <p>Gastric cancer (GC) remains a significant global health burden, with <i>Helicobacter pylori (H. pylori)</i> infection being a major etiological factor. Despite extensive research, a comprehensive overview of the temporal evolution of research output, collaborative networks among countries and institutions, and shifting research foci in this field is lacking.</p> Methods <p>We conducted a bibliometric analysis utilizing the Citexs database and its analytics platform. Literature pertaining to GC and <i>H. pylori</i> published between January 2004 and December 2023 was retrieved and subjected to data mining and visualization to delineate research trends and hotspots.</p> Results <p>Analysis of 12,789 publications revealed a generally upward trend in annual output. The United States was the most productive country, while The American Journal of Gastroenterology was the leading journal. Baylor College of Medicine was the most prolific institution, and Yoshio Yamaoka was the most productive author. Keyword and thematic analysis identified core research areas, including <i>H. pylori</i>, gastritis, the cytotoxin-associated gene A (CagA), and GC itself. At the mechanistic level, current research focuses heavily on genes such as CXCL8, TNF, and NFKB1.</p> Conclusion <p>Future studies should prioritize deeper exploration of these core themes and pivotal signaling pathways to potentially facilitate advances in the prevention and treatment of <i>H. pylori</i>-associated GC.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

A Bibliometric Analysis of Research Trends and Collaborative Networks in Gastric Cancer and Helicobacter Pylori Studies

  • 期刊论文

  • 发表日期：

    2026年1月20日

查看全文
  • Yi Yu,
  • Feihu Bai,
  • Dekui Zhang,
  • Yonggang Tian

摘要

Background

Gastric cancer (GC) remains a significant global health burden, with Helicobacter pylori (H. pylori) infection being a major etiological factor. Despite extensive research, a comprehensive overview of the temporal evolution of research output, collaborative networks among countries and institutions, and shifting research foci in this field is lacking.

Methods

We conducted a bibliometric analysis utilizing the Citexs database and its analytics platform. Literature pertaining to GC and H. pylori published between January 2004 and December 2023 was retrieved and subjected to data mining and visualization to delineate research trends and hotspots.

Results

Analysis of 12,789 publications revealed a generally upward trend in annual output. The United States was the most productive country, while The American Journal of Gastroenterology was the leading journal. Baylor College of Medicine was the most prolific institution, and Yoshio Yamaoka was the most productive author. Keyword and thematic analysis identified core research areas, including H. pylori, gastritis, the cytotoxin-associated gene A (CagA), and GC itself. At the mechanistic level, current research focuses heavily on genes such as CXCL8, TNF, and NFKB1.

Conclusion

Future studies should prioritize deeper exploration of these core themes and pivotal signaling pathways to potentially facilitate advances in the prevention and treatment of H. pylori-associated GC.