Scholarlink

Purpose <p>To identify ethnic differences among women with gestational diabetes mellitus (GDM) in a multiethnic cohort.</p> Methods <p>This observational study included pregnant women with GDM (IADPSG criteria) attending a tertiary centre between January 2020-December 2023, classified according to their ethnic group as White, Black, Asian, or Other. Multivariable logistic and linear regression analyses were performed.</p> Results <p>A total of 633 women (513 White, 64 Black, 32 Asian, and 24 Other/Middle Eastern) were considered eligible for inclusion. Asian women had higher HbA1c than White, Black, and Other (5.5% (37 mmol/mol) vs. 5.1% (32 mmol/mol), 5.2% (33 mmol/mol), and 5.1% (32 mmol/mol), respectively, <i>p</i> &lt; 0.001). The mean birth weight was higher in Asian than White, Black, or Other groups (3429&#xa0;g vs. 3102&#xa0;g, 3279&#xa0;g, and 3159&#xa0;g, respectively, <i>p</i> = 0.05). Insulin therapy during pregnancy was more common in Asian and Other/Middle Eastern than White and Black women (71% and 79.2% vs. 54.5% and 52.4%, respectively, <i>p</i> = 0.03) and was independently associated with Middle Eastern ethnicity (aOR 6.73, 95% CI 1.31–34.46, <i>p</i> = 0.02).</p> Conclusion <p>This study confirmed the presence of ethnic differences in pregnancies complicated by GDM and the higher metabolic burden in Asian and Middle Eastern populations. Ethnicity-specific strategies for GDM prevention and early screening should be implemented.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Ethnic differences in pregnancies complicated by gestational diabetes mellitus: a multiethnic cohort study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年5月5日

查看全文
  • Kleoniki I. Athanasiadou,
  • Georgios Markozannes,
  • Fotini Kanouta,
  • Marina Mitropoulou,
  • Panagiotis Antsaklis,
  • Kalliopi Pappa,
  • Theodora Psaltopoulou,
  • George Daskalakis,
  • Dimitrios G. Goulis,
  • Vasiliki Vasileiou,
  • Stavroula A. Paschou

摘要

Purpose

To identify ethnic differences among women with gestational diabetes mellitus (GDM) in a multiethnic cohort.

Methods

This observational study included pregnant women with GDM (IADPSG criteria) attending a tertiary centre between January 2020-December 2023, classified according to their ethnic group as White, Black, Asian, or Other. Multivariable logistic and linear regression analyses were performed.

Results

A total of 633 women (513 White, 64 Black, 32 Asian, and 24 Other/Middle Eastern) were considered eligible for inclusion. Asian women had higher HbA1c than White, Black, and Other (5.5% (37 mmol/mol) vs. 5.1% (32 mmol/mol), 5.2% (33 mmol/mol), and 5.1% (32 mmol/mol), respectively, p < 0.001). The mean birth weight was higher in Asian than White, Black, or Other groups (3429 g vs. 3102 g, 3279 g, and 3159 g, respectively, p = 0.05). Insulin therapy during pregnancy was more common in Asian and Other/Middle Eastern than White and Black women (71% and 79.2% vs. 54.5% and 52.4%, respectively, p = 0.03) and was independently associated with Middle Eastern ethnicity (aOR 6.73, 95% CI 1.31–34.46, p = 0.02).

Conclusion

This study confirmed the presence of ethnic differences in pregnancies complicated by GDM and the higher metabolic burden in Asian and Middle Eastern populations. Ethnicity-specific strategies for GDM prevention and early screening should be implemented.