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<p>Microbial interactions are crucial for a wide range of processes, including the production of high-quality food and beverages, environmental sustainability through nutrient cycling, waste valorization, bioremediation, and maintaining ecological balance across diverse ecosystems. In natural habitats, microorganisms exhibit competitive and symbiotic relationships, utilizing evolved mechanisms to protect substrates and defend habitats. The combined activity of microorganisms in co-cultures offers synergistic benefits compared to single-microorganism systems, particularly in wastewater treatment and bioproduct production. Microalgal-bacterial coculture processes have gained significant attention due to their high nutrient remediation efficiencies and low-cost wastewater treatment potential. Co-cultures of microalgae with bacteria, yeast, and fungi have shown promise not only in wastewater treatment but also in the production of valuable bioproducts such as biofuels, lactic acid, hydrogen, microbial fuel cells, antibiotics, bioethanol, and biopolymers. This review paper explores the potential of microalgae and other microorganisms in various biotechnological applications. This review highlights the importance of co-cultures in wastewater management, the production of value-added products, challenges faced in co-culture systems, and future research directions. Therefore, integrating microalgae with other microorganisms offers great promise for sustainable biotechnological applications, with the resilience of these systems being crucial for large-scale operations.</p>

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Co-cultures of Microalgae and Other Microorganisms: Wastewater Treatment and Production of Value-Added Bioproducts

  • 期刊论文

  • 发表日期：

    2026年3月3日

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  • Amawish Chaudhry,
  • Tongtong Wang,
  • Chonlong Chio,
  • Dhanushya Thilagam Jeyakumar,
  • Md. Shafiqur Rahman,
  • Zi-Hua Jiang,
  • Shiqing Sun,
  • Wensheng Qin

摘要

Microbial interactions are crucial for a wide range of processes, including the production of high-quality food and beverages, environmental sustainability through nutrient cycling, waste valorization, bioremediation, and maintaining ecological balance across diverse ecosystems. In natural habitats, microorganisms exhibit competitive and symbiotic relationships, utilizing evolved mechanisms to protect substrates and defend habitats. The combined activity of microorganisms in co-cultures offers synergistic benefits compared to single-microorganism systems, particularly in wastewater treatment and bioproduct production. Microalgal-bacterial coculture processes have gained significant attention due to their high nutrient remediation efficiencies and low-cost wastewater treatment potential. Co-cultures of microalgae with bacteria, yeast, and fungi have shown promise not only in wastewater treatment but also in the production of valuable bioproducts such as biofuels, lactic acid, hydrogen, microbial fuel cells, antibiotics, bioethanol, and biopolymers. This review paper explores the potential of microalgae and other microorganisms in various biotechnological applications. This review highlights the importance of co-cultures in wastewater management, the production of value-added products, challenges faced in co-culture systems, and future research directions. Therefore, integrating microalgae with other microorganisms offers great promise for sustainable biotechnological applications, with the resilience of these systems being crucial for large-scale operations.