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<p>Green synthesis is a method in which metal nanoparticles (MNPs) are produced by using biological synthesizing agents, including plant extracts. Copper nanoparticles (CuNPs) are used in a wide range of biological and non-biological sciences due to their unique physical and chemical properties. The research aim is to investigate the potential of producing CuNPs with <i>cinnamon</i> plant extract. Synthesis of CuNPs was done with the hydroalcoholic extract of the <i>cinnamon</i> plant. The Tyndall effect, ultraviolet-visible (UV-Vis), dynamic light Scattering (DLS), fourier transform infrared spectroscopy (FTIR), zeta potential (Zeta-P), raman spectroscopy, field emission scanning electron microscopy (FE-SEM), atomic force microscope (AFM), and x-ray diffraction (XRD) were used for evaluating CuNPs. Cytotoxic effects of nanoparticles (NPs) were measured. The average size of CuNPs is 40&#xa0;nm and spherical, homogeneous, with uniform particle size. The highest cytotoxicity of NPs occurred after 48&#xa0;h. Green synthesis of NPs using edible and medicinal plants such as <i>cinnamon</i> i.e. a suitable option due to its low cost, environmental friendliness, and easy process. In this research, the results indicate that the synthesized CuNPs have strong cytotoxic effects.</p> Graphical Abstract <p></p>

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Green Synthesis and Characterization of Copper Nanoparticles Using Cinnamon (Cinnamomum Zeylanicum L.) Extract with Evaluation of Cytotoxicity Activities

  • 期刊论文

  • 发表日期：

    2026年1月3日

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  • Aida Mehdipour,
  • Mahdieh Ameri Shah reza,
  • Alireza Rasouli,
  • Mohammad Hossein Jafari Baravati,
  • Saeed Shams,
  • Fatemeh Heidari

摘要

Green synthesis is a method in which metal nanoparticles (MNPs) are produced by using biological synthesizing agents, including plant extracts. Copper nanoparticles (CuNPs) are used in a wide range of biological and non-biological sciences due to their unique physical and chemical properties. The research aim is to investigate the potential of producing CuNPs with cinnamon plant extract. Synthesis of CuNPs was done with the hydroalcoholic extract of the cinnamon plant. The Tyndall effect, ultraviolet-visible (UV-Vis), dynamic light Scattering (DLS), fourier transform infrared spectroscopy (FTIR), zeta potential (Zeta-P), raman spectroscopy, field emission scanning electron microscopy (FE-SEM), atomic force microscope (AFM), and x-ray diffraction (XRD) were used for evaluating CuNPs. Cytotoxic effects of nanoparticles (NPs) were measured. The average size of CuNPs is 40 nm and spherical, homogeneous, with uniform particle size. The highest cytotoxicity of NPs occurred after 48 h. Green synthesis of NPs using edible and medicinal plants such as cinnamon i.e. a suitable option due to its low cost, environmental friendliness, and easy process. In this research, the results indicate that the synthesized CuNPs have strong cytotoxic effects.

Graphical Abstract