<p>Due to deficiencies in the oyster supply chain and cold-chain logistics, consumers located far from coastlines find it difficult to obtain fresh, high-quality raw oysters. This paper proposes and designs an intelligent controllable container (ICC) for quality monitoring and maintenance during the transportation of live edible oysters. The method adopts numerical simulation method and phase change materials to optimize temperature control during distribution, uses corona discharge plasma sterilization method to reduce bacterial infection, and integrates multiple sensors for real-time monitoring of the environment to provide a basis for decision making. The experimental results demonstrate that ICC exhibits excellent refrigeration and thermal insulation capabilities and can effectively inhibit bacterial proliferation. During simulated transport trials, ICC reduced the internal temperature to 8 °C within 3 h and maintained for 41 h. The average temperature within the container during the experiment was 6.7 °C. Compared with the control group, the use of plasma reduced the colony count by 2 lg (CFU/g), significantly lowering the total bacterial counts in live oysters during transport and delaying quality deterioration. The container is suitable for various distribution scenarios such as storage, transportation, and sales show, promoting the energy-saving and environmental protection of the oyster supply chain.</p>