Purpose of Review <p>To evaluate the impact of kidney transplantation on sexual function in men and women.</p> Recent Findings <p>A narrative review of the literature was conducted using PubMed in May 2025, including studies published between January 2000 and December 2024 that assessed sexual function before and after kidney transplantation using validated instruments such as the International Index of Erectile Function (IIEF) and the Female Sexual Function Index (FSFI). Of the 155 articles identified, nine studies involving 457 patients were included. Most studies reported an improvement in sexual function after transplantation, sometimes as early as three months post-transplantation. In men, IIEF-5 scores increased by an average of 5 to 7 points, with improvement reported in up to 78% of patients. In women, FSFI scores increased by nearly 8 points, and the proportion reporting an active sexual life rose from 41% to 88%. However, persistent or worsening sexual dysfunction was described in some patients, particularly those of older age, with longer dialysis duration, or receiving specific immunosuppressive therapies.</p> Summary <p>Kidney transplantation is generally associated with improved sexual function in both men and women. Systematic integration of sexual health assessment into pre- and post-transplant follow-up may help better address patients’ needs and expectations.</p>

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Sexual Function After Kidney Transplantation in Men and Women : A Narrative Review

  • Mikael Abi Abdallah,
  • Maxime Vallee,
  • Stessy Kutchukian

摘要

Purpose of Review

To evaluate the impact of kidney transplantation on sexual function in men and women.

Recent Findings

A narrative review of the literature was conducted using PubMed in May 2025, including studies published between January 2000 and December 2024 that assessed sexual function before and after kidney transplantation using validated instruments such as the International Index of Erectile Function (IIEF) and the Female Sexual Function Index (FSFI). Of the 155 articles identified, nine studies involving 457 patients were included. Most studies reported an improvement in sexual function after transplantation, sometimes as early as three months post-transplantation. In men, IIEF-5 scores increased by an average of 5 to 7 points, with improvement reported in up to 78% of patients. In women, FSFI scores increased by nearly 8 points, and the proportion reporting an active sexual life rose from 41% to 88%. However, persistent or worsening sexual dysfunction was described in some patients, particularly those of older age, with longer dialysis duration, or receiving specific immunosuppressive therapies.

Summary

Kidney transplantation is generally associated with improved sexual function in both men and women. Systematic integration of sexual health assessment into pre- and post-transplant follow-up may help better address patients’ needs and expectations.