Purpose of the Review <p>To review epidemiology, pathogenesis, diagnosis, and management of hepatic hydrothorax.</p> Recent Findings <p>Refractory hepatic hydrothorax is an independent predictor of mortality in patients with decompensated cirrhosis. Allocation of Model for End-Stage Liver Disease exception points for patients with refractory hydrothorax was found to be associated with a significant reduction in post liver transplant mortality.</p> Summary <p>Hepatic hydrothorax, pleural effusion in patients with decompensated liver cirrhosis without primary pleural and cardiopulmonary pathology is associated with a high rate of morbidity and mortality. Pathogenesis is a combination of salt and water retention and unidirectional movement of fluid from the peritoneal to the thoracic cavity. Diagnosis relies on pleural fluid analysis and ruling out a primary pleural and cardiopulmonary pathology. Management is complex and requires a stepwise and multidisciplinary approach. All patients with refractory hydrothorax should be evaluated for liver transplant.</p>

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Hepatic Hydrothorax: A Review

  • Abdellatif Ismail,
  • Mohanad Awadalla,
  • Suvisesh Pothuraju,
  • Ashwani K. Singal

摘要

Purpose of the Review

To review epidemiology, pathogenesis, diagnosis, and management of hepatic hydrothorax.

Recent Findings

Refractory hepatic hydrothorax is an independent predictor of mortality in patients with decompensated cirrhosis. Allocation of Model for End-Stage Liver Disease exception points for patients with refractory hydrothorax was found to be associated with a significant reduction in post liver transplant mortality.

Summary

Hepatic hydrothorax, pleural effusion in patients with decompensated liver cirrhosis without primary pleural and cardiopulmonary pathology is associated with a high rate of morbidity and mortality. Pathogenesis is a combination of salt and water retention and unidirectional movement of fluid from the peritoneal to the thoracic cavity. Diagnosis relies on pleural fluid analysis and ruling out a primary pleural and cardiopulmonary pathology. Management is complex and requires a stepwise and multidisciplinary approach. All patients with refractory hydrothorax should be evaluated for liver transplant.