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Purpose of Review <p>Achalasia is characterized by impaired lower esophageal sphincter (LES) relaxation, while Barrett’s esophagus (BE) is typically associated with gastroesophageal reflux disease (GERD) which can occur with excess LES relaxation. This article will provide an overview of the diagnostic challenges, surveillance strategies, and management approaches in the coexistence of these two conditions.</p> Recent Findings <p>Data on outcomes and management of concurrent BE and achalasia are limited. Most commonly, GERD and subsequent BE may occur after therapies for achalasia directed at increasing LES relaxation, and recent papers have focused on GERD and BE outcomes after achalasia therapies.</p> Summary <p>The coexistence of BE and achalasia represents a challenging clinical scenario that requires consideration of the pathophysiology, diagnostic approach, and management strategies for both conditions.</p>

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Management of Barrett’s Esophagus in the Context of Achalasia

  • 期刊论文

  • 发表日期：

    2025年7月28日

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  • Margaret J. Zhou,
  • John O. Clarke

摘要

Purpose of Review

Achalasia is characterized by impaired lower esophageal sphincter (LES) relaxation, while Barrett’s esophagus (BE) is typically associated with gastroesophageal reflux disease (GERD) which can occur with excess LES relaxation. This article will provide an overview of the diagnostic challenges, surveillance strategies, and management approaches in the coexistence of these two conditions.

Recent Findings

Data on outcomes and management of concurrent BE and achalasia are limited. Most commonly, GERD and subsequent BE may occur after therapies for achalasia directed at increasing LES relaxation, and recent papers have focused on GERD and BE outcomes after achalasia therapies.

Summary

The coexistence of BE and achalasia represents a challenging clinical scenario that requires consideration of the pathophysiology, diagnostic approach, and management strategies for both conditions.