Purpose of Review <p>This review examines the evolving role of catheter‐based valvular and structural interventions in cancer patients. We sought to answer whether minimally invasive approaches, including transcatheter aortic valve replacement, mitral valve repair, left atrial appendage occlusion, and patent foramen ovale closure, provide safe and effective treatments in high‐risk oncologic populations.</p> Recent Findings <p>Emerging research indicates that these interventions yield comparable short‐term outcomes in cancer and non‐cancer patients, with reduced procedural complications, lower bleeding risks, and improved recovery times. Studies also suggest that careful patient selection and tailored antithrombotic management are critical, as long‐term survival is affected by the underlying malignancy.</p> Summary <p>Our review concludes that catheter‐based interventions offer significant benefits in managing cardiovascular complications in cancer patients. Future investigations should focus on refining selection criteria, optimizing perioperative care, and evaluating long‐term outcomes to enhance interdisciplinary treatment strategies. These findings pave the way for improved care via a tailored approach to patients with both cancer and cardiovascular disease.</p>