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<p>Ambient air pollution represents the leading contributor to the global burden of respiratory diseases. Thus, it’s necessary to evaluate the additional hospitalization burden for respiratory diseases resulting from air pollutants among different population subgroups. Both single-pollutant and multi-pollutant Generalized Additive Model (GAM) analyses were performed to investigate the correlation between air pollutants and hospitalizations for respiratory disease in total population, males, females, people &lt; 65 years old and people ≥ 65 years old, in Hengyang, China from 2019 to 2023. We found that in single-pollutant GAMs, the cumulative concentration over 2 days (lag02) of SO<sub>2</sub> and the concentration with a one-day lag (lag1) of O<sub>3</sub> for respiratory diseases hospitalizations showed more effects on total population. And the excessive risk (ER) were 6.43 (1.40, 11.71) and 0.52 (0.02, 1.03). The lag02 ER of SO<sub>2</sub> were 7.85 (1.85, 14.20) in males. In females, the lag1 ER of NO<sub>2</sub> was 2.85 (0.27, 5.50). In people &lt; 65 years old, the lag02 ER of SO<sub>2</sub> and the lag1 ER of O<sub>3</sub> were 5.81 (0.24, 11.68) and 0.76 (0.20, 1.32). And in people ≥ 65 years old, the lag02 ER of SO<sub>2</sub> was 7.90 (0.36, 16.01). After including PM<sub>2.5</sub> into GAMs, we obtained similar results. In conclusions, exposure to air pollutants SO<sub>2</sub>, NO<sub>2</sub> and O<sub>3</sub> had lag effects on the increased hospitalizations for respiratory diseases. Specifically, females were more susceptible to the impact of NO<sub>2</sub>, while males were more susceptible to the impact of SO<sub>2</sub>. And people &lt; 65 years old were more sensitive to O<sub>3</sub> compared to those ≥ 65 years old.</p>

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The association between ambient air pollutants and hospitalizations for respiratory diseases in Hengyang, China, from 2019 to 2023: a time-series study to identify sensitive populations

  • 期刊论文

  • 发表日期：

    2025年9月5日

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  • An Ning,
  • Liu Xiuying,
  • Zhang Xinge,
  • Lv Lingshuang,
  • Zhang Min,
  • Xia Xin,
  • Gao Lidong

摘要

Ambient air pollution represents the leading contributor to the global burden of respiratory diseases. Thus, it’s necessary to evaluate the additional hospitalization burden for respiratory diseases resulting from air pollutants among different population subgroups. Both single-pollutant and multi-pollutant Generalized Additive Model (GAM) analyses were performed to investigate the correlation between air pollutants and hospitalizations for respiratory disease in total population, males, females, people < 65 years old and people ≥ 65 years old, in Hengyang, China from 2019 to 2023. We found that in single-pollutant GAMs, the cumulative concentration over 2 days (lag02) of SO2 and the concentration with a one-day lag (lag1) of O3 for respiratory diseases hospitalizations showed more effects on total population. And the excessive risk (ER) were 6.43 (1.40, 11.71) and 0.52 (0.02, 1.03). The lag02 ER of SO2 were 7.85 (1.85, 14.20) in males. In females, the lag1 ER of NO2 was 2.85 (0.27, 5.50). In people < 65 years old, the lag02 ER of SO2 and the lag1 ER of O3 were 5.81 (0.24, 11.68) and 0.76 (0.20, 1.32). And in people ≥ 65 years old, the lag02 ER of SO2 was 7.90 (0.36, 16.01). After including PM2.5 into GAMs, we obtained similar results. In conclusions, exposure to air pollutants SO2, NO2 and O3 had lag effects on the increased hospitalizations for respiratory diseases. Specifically, females were more susceptible to the impact of NO2, while males were more susceptible to the impact of SO2. And people < 65 years old were more sensitive to O3 compared to those ≥ 65 years old.