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<p>Troponins are an integral part of the diagnosis of acute coronary syndromes in cardiology. It is also useful in many other acute cardiological conditions, such as acute pulmonary embolism. In cardio-oncology, it is part of the definition of either cancer disease or cancer therapy related cardiovascular toxicity. Change in troponin value is one of the diagnostic criteria for mild and moderate cancer therapy related cardiac dysfunction. Diagnosis of myocarditis is also based on troponin elevation. However, an ideal cut-off points for precise diagnostic value and indication for cardiology treatment have not yet been defined.It is still difficult to make therapeutic decisions in cardio-oncology about the initiation, intensification or modification of cardiac therapy based on the dynamics of troponin changes.</p>

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Role of Troponins in CardioOncology

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月20日

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  • Jakub Homotnik,
  • Sabina Mędrek,
  • Kasper Rolek,
  • Magdalena Zaborowska-Szmit,
  • Sebastian Szmit

摘要

Troponins are an integral part of the diagnosis of acute coronary syndromes in cardiology. It is also useful in many other acute cardiological conditions, such as acute pulmonary embolism. In cardio-oncology, it is part of the definition of either cancer disease or cancer therapy related cardiovascular toxicity. Change in troponin value is one of the diagnostic criteria for mild and moderate cancer therapy related cardiac dysfunction. Diagnosis of myocarditis is also based on troponin elevation. However, an ideal cut-off points for precise diagnostic value and indication for cardiology treatment have not yet been defined.It is still difficult to make therapeutic decisions in cardio-oncology about the initiation, intensification or modification of cardiac therapy based on the dynamics of troponin changes.