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Background <p>Liver tissue ectopia occurs in less than 1% of cases, typically in areas adjacent to the liver, such as the gallbladder or spleen. Liver tissue ectopia within the heart is even rarer. This paper reports a case of histopathologically confirmed liver tissue ectopia in the right atrium. Additionally, it summarises the characteristics of twelve previously reported similar cases, offering new insights into liver tissue ectopia within cardiac chambers.</p> Case presentation <p>The patient is a 31-year-old female who is obese and has had three pregnancies and three caesarean sections. She was previously healthy. Main complaint: intermittent palpitations. Physical examination revealed no significant abnormalities. A cardiac ultrasound scan showed a solid mass in the right atrium near the opening of the inferior vena cava. The patient underwent cardiac surgery. Intraoperative exploration revealed an ectopic liver tissue mass measuring 30&#xa0;mm × 20&#xa0;mm at the junction of the right atrium and the inferior vena cava. Routine histopathology revealed the mass to be a well-differentiated, mature hepatic tissue with clear lobular architecture. Some hepatocytes showed oedematous degeneration, while others exhibited enlarged portal areas with minor bile duct hyperplasia.</p> Conclusion <p>Intracardiac liver tissue ectopia is an extremely rare condition. Through case reports and a review of the literature, we have identified middle-aged and young female patients as potentially being at high risk of developing this disease.</p>

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Benign hepatocellular mass in the right atrium: a rare case of ectopic liver tissue and literature review

  • 期刊论文

  • 发表日期：

    2026年4月21日

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  • Mingjie Xie,
  • Zhongda Yao,
  • Xinyi Yu,
  • Yu Pei,
  • Weiwei Zhang,
  • Gang Su

摘要

Background

Liver tissue ectopia occurs in less than 1% of cases, typically in areas adjacent to the liver, such as the gallbladder or spleen. Liver tissue ectopia within the heart is even rarer. This paper reports a case of histopathologically confirmed liver tissue ectopia in the right atrium. Additionally, it summarises the characteristics of twelve previously reported similar cases, offering new insights into liver tissue ectopia within cardiac chambers.

Case presentation

The patient is a 31-year-old female who is obese and has had three pregnancies and three caesarean sections. She was previously healthy. Main complaint: intermittent palpitations. Physical examination revealed no significant abnormalities. A cardiac ultrasound scan showed a solid mass in the right atrium near the opening of the inferior vena cava. The patient underwent cardiac surgery. Intraoperative exploration revealed an ectopic liver tissue mass measuring 30 mm × 20 mm at the junction of the right atrium and the inferior vena cava. Routine histopathology revealed the mass to be a well-differentiated, mature hepatic tissue with clear lobular architecture. Some hepatocytes showed oedematous degeneration, while others exhibited enlarged portal areas with minor bile duct hyperplasia.

Conclusion

Intracardiac liver tissue ectopia is an extremely rare condition. Through case reports and a review of the literature, we have identified middle-aged and young female patients as potentially being at high risk of developing this disease.