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Background <p>Cognitive abilities are important for mobility functions in individuals with amputation.</p> Aims <p>To investigate the association between cognitive function and physical performance in established users of a lower limb prosthesis.</p> Methods <p>This prospective cross-sectional study was included established users of a lower limb prosthesis (<i>N</i> = 62; mean age ± SD, 41.33 ± 14.76&#xa0;years). The Montreal Cognitive Assessment was used to evaluate cognitive function. The Timed Up and Go Test under single-task and dual-task conditions, the Four Square Step Test, and the 3-m Backward Walk Test were used for physical performance assessment.</p> Results <p>An independent association was found of the Montreal Cognitive Assessment to the dual task Timed Up and Go Test (AdjR<sup>2</sup> = 0.168, <i>p</i> = 0.003), the Four Square Step Test (AdjR<sup>2</sup> = 0.25, <i>p</i> = 0.003) and the 3-m Backward Walk Test (AdjR<sup>2</sup> = 0.159, <i>p</i> = 0.032). An increase of 1 point in the Montreal Cognitive Assessment was associated with a reduction of 0.681 s (95% CI, 1.116–0.246) in the the dual task Timed Up and Go Test, 0.378 s (95% CI, 0.617–0.138) in the Four Square Step Test, and 0.255 s (95% CI, 0.487–0.022) in the 3-m Backward Walk Test.</p> Conclusions <p>The results of this study revealed an independent association between global cognitive function and functional mobility under dual-task conditions, dynamic balance, and backward walking performance in established users of a lower limb prosthesis. These results emphasize that cognitive functions should be taken into account in interventions aimed at improving challenging physical performance in established users of a lower limb prosthesis.</p>

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The association between cognitive function and physical performance in established users of a lower limb prosthesis

  • 期刊论文

  • 发表日期：

    2025年8月15日

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  • Senem Demirdel,
  • Rahime Yılmaz,
  • Selma Küçük,
  • Osman Söyler

摘要

Background

Cognitive abilities are important for mobility functions in individuals with amputation.

Aims

To investigate the association between cognitive function and physical performance in established users of a lower limb prosthesis.

Methods

This prospective cross-sectional study was included established users of a lower limb prosthesis (N = 62; mean age ± SD, 41.33 ± 14.76 years). The Montreal Cognitive Assessment was used to evaluate cognitive function. The Timed Up and Go Test under single-task and dual-task conditions, the Four Square Step Test, and the 3-m Backward Walk Test were used for physical performance assessment.

Results

An independent association was found of the Montreal Cognitive Assessment to the dual task Timed Up and Go Test (AdjR2 = 0.168, p = 0.003), the Four Square Step Test (AdjR2 = 0.25, p = 0.003) and the 3-m Backward Walk Test (AdjR2 = 0.159, p = 0.032). An increase of 1 point in the Montreal Cognitive Assessment was associated with a reduction of 0.681 s (95% CI, 1.116–0.246) in the the dual task Timed Up and Go Test, 0.378 s (95% CI, 0.617–0.138) in the Four Square Step Test, and 0.255 s (95% CI, 0.487–0.022) in the 3-m Backward Walk Test.

Conclusions

The results of this study revealed an independent association between global cognitive function and functional mobility under dual-task conditions, dynamic balance, and backward walking performance in established users of a lower limb prosthesis. These results emphasize that cognitive functions should be taken into account in interventions aimed at improving challenging physical performance in established users of a lower limb prosthesis.