<p>Hydrogen is a potent reducing gas which has been applied to the reduction of iron ore sinter for sustainable ironmaking without CO₂ emissions. This study offered a systematic review of the reduction of iron ore sinter by hydrogen based on the analyses of the physicochemical characteristics of iron ore sinter and the factors that affect the reduction process, including sinter phase components, basicity, H₂ concentration, reduction temperature, and reduction time. In comparison with CO, H₂ can promote the reduction and reduce the disintegration index of iron ore sinter by 1–2% at the same reduction temperature mainly attributed to its higher diffusivity. Despite several challenges, including high energy consumption because of the high temperature required for H₂ reduction of iron ore sinter and the high price of H₂, the low utilization ratio of hydrogen due to its greater reaction rate, the integral reduction disintegration of the sinter caused by the high diffusivity of H₂, and a shortage of hydrogen for reduction owing to current high H₂ production cost, which restrains the efficient reduction of iron ore sinter by H₂, potential solutions, including selecting the proper temperature range for reduction at around 810°C, enhancing the diffusion of hydrogen by adjusting the reaction temperature and optimizing the gas mixing ratio, controlling H₂ concentration in the range 10–15 vol.%, and creating industrial-scale demand for hydrogen from the perspective of the implement of the carbon neutrality policy, are provided as guidance for its application.</p>