Effects of Micro-/Nano-Textured and HA/CS Coating Composite Structures on Ti6AL4V Surfaces' Biological Properties
摘要
Hydroxyapatite (HA), a ceramic material closely resembling the composition and structure of human bone, and chitosan (CS), the only natural alkaline polysaccharide, were employed in this study. Electrophoretic deposition was utilized to investigate coatings formed from suspensions with varying HA/CS ratios, and the results indicated that, when the HA content was 1 g and the CS content was 0.5 g, the overall properties of the coating were significantly enhanced. Additionally, fiber laser processing was applied to create microstructures, and a comparative analysis was performed to determine the optimal processing parameters for achieving the best morphology. Anodic oxidation was used to fabricate 70-nm nanotubes on the implant surface, which provided the maximum contact area with newly formed bone tissue and exhibited superior osteogenic potential. Furthermore, hydrophilicity analysis was conducted to compare different micro- and nanostructure ratios, revealing that a 1:3.5 ratio of micro- to nanostructures exhibited excellent properties. A composite coating was subsequently formed on this structure, and the composite’s corrosion resistance, adhesion strength, hydrophilicity, and cell adhesion properties were systematically evaluated.