<p>Coral sand, commonly found in offshore and marine engineering, is highly susceptible to seismic threats, with liquefaction being a prominent form of seismic damage. Traditional liquefaction assessment methods for terrestrial soils are not applicable to coral sand sites. To address the lack of coral sand liquefaction data, a coupled analysis combining optimized undrained triaxial cyclic tests on saturated coral sand with shear wave velocity (<i>V</i>_s) measurements is presented and a characterization relationship between shear wave velocity and liquefaction strength for coral sand is proposed. Further, by incorporating engineering experience and considering two key parameters commonly used in Chinese liquefaction assessments—groundwater level and burial depth—a technical process for liquefaction assessment in saturated coral sand layers is established. Comparative analysis with existing methods supports the validity of the proposed approach. The method, which was tested retrospectively on Hawaii’s Kawaihae Harbor following a <i>M</i>_w 6.7 earthquake in 2006, showed results consistent with actual conditions. This approach is expected to improve as more seismic data becomes available, and it may also inform the development of liquefaction assessment methods for broadly graded coral soil sites.</p>