Let G be a locally compact group, \(\Phi _1, \Phi _2\) be Young functions and \(\nu , \omega \) be moderate weight functions on G. In this paper, we investigate inclusion relations between the Orlicz amalgam spaces \(W(L_{\nu }^{\Phi _1} (G), L_{\omega }^{\Phi _2} (G))\) with respect to Young functions, weights where the local and global components are the weighted Orlicz spaces \(L_{\nu }^{\Phi _1}(G)\) and \(L_{\omega }^{\Phi _2}(G)\) , respectively. We also compare Orlicz amalgam spaces when G is a compact and discrete group. Our study generalizes and unifies the results that have been obtained for the Lebesgue spaces and the weighted Lebesgue spaces.