Purpose <p>Employers and professionals can support cancer survivors during sick leave and return to work (RTW). However, they often face challenges in providing RTW support and existing interventions targeted at them are scarce and show limited effectiveness<i>.</i> This study aims to examine information and support needs of employers and professionals regarding sick leave and RTW of cancer survivors.</p> Methods <p>For this scoping review, studies published between 2014 and 2024 were systematically searched across five databases. Included studies had to (1) involve employers (direct supervisors or HR managers) or professionals (healthcare and occupational health professionals); (2) use a qualitative, quantitative, or mixed method study design; and (3) report at least one information or support need in the results. Identified needs were qualitatively synthesized using the Arena in work disability prevention model.</p> Results <p>Forty studies from 15 countries identified a diversity of needs across the personal, healthcare, workplace, and legislative systems. Employers and professionals need information and support on late effects of cancer and its treatment, providing RTW support, legislation, and multidisciplinary collaboration. Additionally, employers need information on communication, while professionals need support in assessing cancer survivors’ work capacity and functional abilities.</p> Conclusions <p>Diverse information and support needs were identified. Some needs were universal, while others were context-dependent, as they depended on country-specific legislation. Multidisciplinary collaboration among stakeholders is essential, and contextual factors should be integrated into future interventions.</p> Implications for cancer survivors <p>Addressing employers’ and professionals’ needs enables more comprehensive and personalized support for cancer survivors and strengthens RTW support systems.</p>