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Purpose <p>This study evaluated the early clinical and echocardiographic outcomes of mitral valve (MV) repair using the Physio Flex Annuloplasty Ring for mitral regurgitation (MR) of various etiologies.</p> Methods <p>We retrospectively analyzed 185 patients who underwent MV repair using Physio Flex Annuloplasty Ring between July 2020 and October 2024. Degenerative MR was the most common type (n = 94), followed by functional MR (n = 79). Severe and moderate MR were observed in 126 and 59 patients, respectively.</p> Results <p>Artificial chordal reconstruction, leaflet resection, and folding plasty were performed in 61 (33.0%), 21 (11.4%), and 13 (7.0%) patients, respectively, whereas ring annuloplasty alone was performed in 64 (34.6%) patients. The median ring size was 30&#xa0;mm&#xa0;(interquartile range, 30–32mm). The operative mortality rate was 2.2%. Postoperatively, no/trivial and mild MR were observed in 162 (87.6%) and 18 (9.7%) patients, respectively. Left ventricular end-diastolic and end-systolic diameters significantly decreased from 51 ± 8&#xa0;mm to 47 ± 7&#xa0;mm and from 34 ± 9&#xa0;mm to 32 ± 8&#xa0;mm, respectively (P &lt; 0.001). The right ventricular systolic pressure also decreased (33 ± 13&#xa0;mmHg to 29 ± 10&#xa0;mmHg; P &lt; 0.001). Functional mitral stenosis (mean transmitral pressure gradient&#xa0;of ≥ 5&#xa0;mmHg) occurred in 13 patients.</p> Conclusion <p>MV repair using the Physio Flex Annuloplasty Ring provides effective MR control and satisfactory early outcomes, with an acceptable incidence of functional mitral stenosis.</p>

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Initial experience of mitral valve repair using the Physio Flex Annuloplasty Ring

  • 期刊论文

  • 发表日期：

    2025年7月18日

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  • Kosaku Nishigawa,
  • Shuhei Kawamoto,
  • Kazuki Morooka,
  • Motoharu Shimozawa,
  • Fumiya Haba,
  • Shunya Ono,
  • Takeyuki Kanemura

摘要

Purpose

This study evaluated the early clinical and echocardiographic outcomes of mitral valve (MV) repair using the Physio Flex Annuloplasty Ring for mitral regurgitation (MR) of various etiologies.

Methods

We retrospectively analyzed 185 patients who underwent MV repair using Physio Flex Annuloplasty Ring between July 2020 and October 2024. Degenerative MR was the most common type (n = 94), followed by functional MR (n = 79). Severe and moderate MR were observed in 126 and 59 patients, respectively.

Results

Artificial chordal reconstruction, leaflet resection, and folding plasty were performed in 61 (33.0%), 21 (11.4%), and 13 (7.0%) patients, respectively, whereas ring annuloplasty alone was performed in 64 (34.6%) patients. The median ring size was 30 mm (interquartile range, 30–32mm). The operative mortality rate was 2.2%. Postoperatively, no/trivial and mild MR were observed in 162 (87.6%) and 18 (9.7%) patients, respectively. Left ventricular end-diastolic and end-systolic diameters significantly decreased from 51 ± 8 mm to 47 ± 7 mm and from 34 ± 9 mm to 32 ± 8 mm, respectively (P < 0.001). The right ventricular systolic pressure also decreased (33 ± 13 mmHg to 29 ± 10 mmHg; P < 0.001). Functional mitral stenosis (mean transmitral pressure gradient of ≥ 5 mmHg) occurred in 13 patients.

Conclusion

MV repair using the Physio Flex Annuloplasty Ring provides effective MR control and satisfactory early outcomes, with an acceptable incidence of functional mitral stenosis.