<p>Evidence describing outcomes of Retzius-sparing robot-assisted radical prostatectomy (RS-RARP) in men who previously underwent transurethral resection of the prostate (p-TURP) is limited. This study aimed to characterize perioperative performance, cancer control, and the pattern of urinary continence recovery (UCR) in this subgroup.&#xa0;We analyzed all RS-RARP procedures conducted by a single high-volume surgeon at a European tertiary center from April 2016 till December 2023. Patients were categorized according to the presence or absence of prior p-TURP. To minimize baseline differences, a 5:1 propensity score matching model was used.&#xa0;Among 542 men who met the inclusion criteria, 29 (17%) had previously undergone p-TURP. Operative metrics including blood loss, duration of surgery, hospital stay, time to catheter removal and postoperative complications did not differ significantly between the two groups (all <i>p</i> ≥ 0.1). Rates of positive surgical margins (17% vs. 17%, <i>p</i> = 0.9), PSA persistence (14% vs. 8%, <i>p</i> = 0.3), biochemical recurrence (10% vs. 14%, <i>p</i> = 0.8), and need for additional treatment (7% vs. 12%, <i>p</i> = 0.5) were likewise comparable. Early UCR both immediately after catheter removal and during the first months was slower in the p-TURP cohort; however, by 12 months all patients with prior TURP were continent, mirroring the continence rate observed in the control group (100% vs. 95%, <i>p</i> = 0.4).&#xa0;This study suggests that men with prior TURP experience perioperative and oncologic outcomes comparable to TURP-naive patients following RS-RARP.</p>

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Retzius-sparing robot-assisted radical prostatectomy after previous trans-urethral resection of the prostate: an analysis of perioperative, oncological and functional outcomes

  • Karen Fransis,
  • Quinten Bogaerts,
  • Gunter De Win,
  • Stefan De Wachter,
  • Piet Dirix

摘要

Evidence describing outcomes of Retzius-sparing robot-assisted radical prostatectomy (RS-RARP) in men who previously underwent transurethral resection of the prostate (p-TURP) is limited. This study aimed to characterize perioperative performance, cancer control, and the pattern of urinary continence recovery (UCR) in this subgroup. We analyzed all RS-RARP procedures conducted by a single high-volume surgeon at a European tertiary center from April 2016 till December 2023. Patients were categorized according to the presence or absence of prior p-TURP. To minimize baseline differences, a 5:1 propensity score matching model was used. Among 542 men who met the inclusion criteria, 29 (17%) had previously undergone p-TURP. Operative metrics including blood loss, duration of surgery, hospital stay, time to catheter removal and postoperative complications did not differ significantly between the two groups (all p ≥ 0.1). Rates of positive surgical margins (17% vs. 17%, p = 0.9), PSA persistence (14% vs. 8%, p = 0.3), biochemical recurrence (10% vs. 14%, p = 0.8), and need for additional treatment (7% vs. 12%, p = 0.5) were likewise comparable. Early UCR both immediately after catheter removal and during the first months was slower in the p-TURP cohort; however, by 12 months all patients with prior TURP were continent, mirroring the continence rate observed in the control group (100% vs. 95%, p = 0.4). This study suggests that men with prior TURP experience perioperative and oncologic outcomes comparable to TURP-naive patients following RS-RARP.