Scholarlink

<p>The purpose of this study is to evaluate the effects of robot-assisted partial nephrectomy versus open partial nephrectomy on perioperative outcomes, complications, and glomerular filtration rate in renal tumor patients with chronic kidney disease (CKD). A comprehensive systematic review was conducted across several peer-reviewed electronic databases, such as PubMed, Cochrane Library, Embase, and Web of Science. The search encompassed publications in all languages up to October 2025. Following the exclusion of non-relevant records such as reviews and commentaries, the eligible studies were subjected to meta-analysis. This was performed using Review Manager, employing weighted mean differences (WMD) and odds ratios (OR) for the evaluation of continuous and dichotomous variables, respectively. The review protocol was registered with PROSPERO (CRD No. 420251207798). Pooled data from 868 patients across three retrospective cohort studies revealed that RAPN offers a favorable profile compared to OPN for patients with renal tumors and chronic renal insufficiency. The benefits of RAPN included minimized blood loss (MD -148.8, 95% CI [-235.61, -62.16]; <i>p</i> = 0.0008), reduced hospitalization duration (MD -2.73, 95% CI [-4.24, -1.23]; <i>p</i> = 0.0004), and superior postoperative glomerular filtration rate recovery (MD 1.77, 95% CI [1.37, 2.18]; <i>p</i> &lt; 0.00001). Conversely, no statistically significant differences were identified for other evaluated parameters, including operative time, transfusion rate, complication incidence, ischemia time, or positive surgical margins. In conclusion, this meta-analysis of three retrospective studies suggests that robotic-assisted surgery holds promise as a preferable treatment strategy. However, the strength of this conclusion is limited by the small number of studies, their retrospective design, and notable clinical heterogeneity (e.g., in baseline renal function). To definitively establish these benefits, confirmation from future large-scale, high-quality randomized controlled trials is necessary.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Robot-assisted versus open partial nephrectomy in renal tumor patients with chronic kidney disease: a meta-analysis of renal functional and perioperative outcomes

  • 期刊论文

  • 发表日期：

    2025年12月29日

查看全文
  • Chongjian Wang,
  • Erhao Bao,
  • Sheng Li,
  • Chengcheng Pang,
  • Yang Yang,
  • Jing Liu

摘要

The purpose of this study is to evaluate the effects of robot-assisted partial nephrectomy versus open partial nephrectomy on perioperative outcomes, complications, and glomerular filtration rate in renal tumor patients with chronic kidney disease (CKD). A comprehensive systematic review was conducted across several peer-reviewed electronic databases, such as PubMed, Cochrane Library, Embase, and Web of Science. The search encompassed publications in all languages up to October 2025. Following the exclusion of non-relevant records such as reviews and commentaries, the eligible studies were subjected to meta-analysis. This was performed using Review Manager, employing weighted mean differences (WMD) and odds ratios (OR) for the evaluation of continuous and dichotomous variables, respectively. The review protocol was registered with PROSPERO (CRD No. 420251207798). Pooled data from 868 patients across three retrospective cohort studies revealed that RAPN offers a favorable profile compared to OPN for patients with renal tumors and chronic renal insufficiency. The benefits of RAPN included minimized blood loss (MD -148.8, 95% CI [-235.61, -62.16]; p = 0.0008), reduced hospitalization duration (MD -2.73, 95% CI [-4.24, -1.23]; p = 0.0004), and superior postoperative glomerular filtration rate recovery (MD 1.77, 95% CI [1.37, 2.18]; p < 0.00001). Conversely, no statistically significant differences were identified for other evaluated parameters, including operative time, transfusion rate, complication incidence, ischemia time, or positive surgical margins. In conclusion, this meta-analysis of three retrospective studies suggests that robotic-assisted surgery holds promise as a preferable treatment strategy. However, the strength of this conclusion is limited by the small number of studies, their retrospective design, and notable clinical heterogeneity (e.g., in baseline renal function). To definitively establish these benefits, confirmation from future large-scale, high-quality randomized controlled trials is necessary.