Biogenic synthesis of metal/metal oxide nanoparticles using essential oils and their antimicrobial potential
摘要
Various synthetic antibiotics have been used to cure microbial pathogenesis, which is the prevalent reason for fatalities all over the world. But, the continuous use of synthetic antibiotics resulted in the development of antibiotic resistance in the targeted microbes, which further creates a new problem for the current treatment line. Along with this, the use of antibiotics is also associated with certain side effects, such as gastrointestinal and dermatological complications. Essential oils, being secondary metabolites of plants, have wide spread usage as antimicrobial agents. But, certain limitations of essential oils such as volatile nature, hydrophobicity, low solubility in water, low stability and high cost of production restrict their usage as antimicrobial agents. The green synthesis of nanoparticles, where various secondary metabolites present in plant essential oils reduce metal ions, is a quick and simple single step procedure that needs no harmful chemicals. These metal nanoparticles loaded with essential oils improve the efficacy of essential oils by their higher loading capacity, controlled release of bioactive compounds, increased bioavailability of less soluble constituents, protection of bioactive components from oxidation and increased solubility of essential oil in aqueous phase. This review aims to provide insight into the green synthesis of metal/metal oxide nanoparticles using essential oils with their usefulness as antimicrobial agents.