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Background <p>Severe obesity and its associated comorbidities in adolescents pose a growing global health challenge. Although laparoscopic sleeve gastrectomy (LSG) has emerged as an effective treatment option, clinical evidence in Asian populations remains limited. Therefore, we aimed to evaluate the short-term clinical and metabolic outcomes of LSG in severely obese Korean adolescents.</p> Methods <p>Between 2020 and 2025, a total of 1,824 bariatric surgeries were conducted at Incheon Sejong Hospital, among which 24 adolescent cases of LSG were identified for retrospective analysis. Demographic characteristics, body composition, perioperative laboratory findings, and postoperative weight loss outcomes were analyzed.</p> Results <p>A total of 24 adolescent patients who underwent LSG for severe obesity were included. At 12 months postoperatively, patients achieved significant weight loss, with a mean percentage of excess weight loss of 84.12% and percentage of excess body mass index loss of 84.43%. Body composition analysis at 12 months postoperatively revealed a 51.12% reduction in fat mass, whereas muscle mass was relatively preserved (16.67% loss). Metabolic profiles improved significantly, as evidenced by a decrease in triglycerides (167.3 to 67.9&#xa0;mg/dL, <i>p</i> = 0.001) and fasting C-peptide (4.0 to 2.4&#xa0;mg/dL, <i>p</i> = 0.009). Regarding hepatic steatosis and fibrosis, the controlled attenuation parameter and liver stiffness measurement decreased from 337 to 246 dB/m and 7.1 to 5.1&#xa0;kPa, respectively.</p> Conclusions <p>LSG demonstrated favorable safe and feasible intervention for Korean adolescents with severe obesity within this cohort, achieving significant weight loss and rapid improvements in metabolic and hepatic parameters within the first postoperative year.</p>

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Short-Term Clinical and Metabolic Outcomes of Laparoscopic Sleeve Gastrectomy in Korean Adolescents with Severe Obesity: A Retrospective Analysis

  • 期刊论文

  • 发表日期：

    2026年7月11日

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  • Jeong-Seon Lee,
  • Sungbae Lee,
  • Sungwoo Jung,
  • Ji Hyung Kim,
  • Okjoo Lee

摘要

Background

Severe obesity and its associated comorbidities in adolescents pose a growing global health challenge. Although laparoscopic sleeve gastrectomy (LSG) has emerged as an effective treatment option, clinical evidence in Asian populations remains limited. Therefore, we aimed to evaluate the short-term clinical and metabolic outcomes of LSG in severely obese Korean adolescents.

Methods

Between 2020 and 2025, a total of 1,824 bariatric surgeries were conducted at Incheon Sejong Hospital, among which 24 adolescent cases of LSG were identified for retrospective analysis. Demographic characteristics, body composition, perioperative laboratory findings, and postoperative weight loss outcomes were analyzed.

Results

A total of 24 adolescent patients who underwent LSG for severe obesity were included. At 12 months postoperatively, patients achieved significant weight loss, with a mean percentage of excess weight loss of 84.12% and percentage of excess body mass index loss of 84.43%. Body composition analysis at 12 months postoperatively revealed a 51.12% reduction in fat mass, whereas muscle mass was relatively preserved (16.67% loss). Metabolic profiles improved significantly, as evidenced by a decrease in triglycerides (167.3 to 67.9 mg/dL, p = 0.001) and fasting C-peptide (4.0 to 2.4 mg/dL, p = 0.009). Regarding hepatic steatosis and fibrosis, the controlled attenuation parameter and liver stiffness measurement decreased from 337 to 246 dB/m and 7.1 to 5.1 kPa, respectively.

Conclusions

LSG demonstrated favorable safe and feasible intervention for Korean adolescents with severe obesity within this cohort, achieving significant weight loss and rapid improvements in metabolic and hepatic parameters within the first postoperative year.