Background <p>Research shows that a positive doctor-patient relationship plays an important role in patient outcomes. However, the influence of their communication during the pre-surgery preparatory consultation (PC) for metabolic and bariatric surgery (MBS) remains unclear. The goal of this study was to inspect the association between patients’ perceptions of doctor-patient communication (DPC) in the PC for MBS and the results of the MBS.</p> Methods <p>This prospective cross-sectional study included 89 adult patients undergoing MBS at a hospital. Before the surgery, patients’ perspectives regarding DPC were assessed with the Communication Assessment Tool (CAT). One month after the surgery, participants’ levels of well-being were assessed through the 36-Item Short Form Survey (SF-36). Other clinical data were obtained through patients’ electronic records. Data were analyzed with regression models.</p> Results <p>In the adjusted models, associations&#xa0;with the quality of&#xa0;doctor-patient communication (<i>p</i> &lt; 0.05) were found for the following outcomes: weight loss, body mass index decrease, and patient well-being regarding bodily pain and social functioning. Significant differences (<i>p</i> &lt; 0.05) were also found for digestive complaints and for patient perception of physician post-surgery support.</p> Conclusions <p>DPC in the preparatory consultation has a positive effect on the clinical results of MBS. More studies are necessary for inspection of the generalizability of these findings.</p> Graphical Abstract <p></p>