<p>The demand for biostabilization and preservation of bioactive peptides, cell culture, and other functional ingredients has grown dramatically due to increase in popularity of functional food, nutraceuticals, and other healthy dietary supplements. EHD preservation through drying, encapsulation, and immobilization are gaining attention due to their compatibility and sustainability. The EHD method is turning out to be a new-generation solution for preserving and biostabilizing bioactives and thus increasing their stability. This review mainly focuses on the impacts of different EHD technologies on the stability of products under different processing and environmental conditions. The review also focuses on the influence of electric fields on chemicals, molecular structure, and structural integrity of different biomolecules under different EHD processing methods. Different polymers and encapsulation matrices, types of encapsulations, and their effect on the stability and compatibility of encapsulates are discussed in this literature. The findings from this review could serve as a valuable resource for researchers in formulating various nutraceuticals, functional foods, probiotics, and tissue engineering using EHD techniques. EHD drying enhances the functional and nutritional value of commodities by protecting and preserving principal components without degradation. Moreover, EHD encapsulation improves stability and structural integrity under various processing and environmental conditions compared to other encapsulation techniques. Advanced encapsulation EHD coaxial encapsulation enhanced the viability of microbial cell culture and improved the invitro release kinetics. The EHD ink jet printing possesses immense potential for tissue engineering, scaffolding, cultured meat production, biosensing, immobilization over various matrices, and active packaging applications.</p> Graphical abstract <p></p>