Scholarlink

<p>Research suggests that emerging adults with type 1 diabetes demonstrate many neural differences from their peers, including poorer executive functioning. However, limited research has examined whether these differences are associated with alterations in neural activation and whether brain processes vary depending on illness management (i.e., hemoglobin A1c). Using functional magnetic resonance imaging, we examined whether emerging adults with type 1 diabetes showed differences in in executive functioning-related neural activation compared to age-matched peers without type 1 diabetes. We found that, although participants with type 1 diabetes demonstrated similar behavioral inhibition performance to their peers, they showed comparatively greater activation in several interconnected executive functioning-related brain regions, including the left frontal, temporal, and insular regions. We did not find an association between hemoglobin HbA1c and executive function-related neural activation. These findings suggests that individuals with type 1 diabetes likely exert <i>greater</i> neural “effort” in executive functioning-related brain regions to achieve similar levels of inhibitory control when compared to peers without type 1 diabetes.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Executive functioning-related neural processes in emerging adults with type 1 diabetes

  • 期刊论文

  • 发表日期：

    2026年3月16日

查看全文
  • Chad D. Jensen,
  • Hannah M. McDaniel,
  • Monica C. Martinez,
  • Christopher M. Jones,
  • C. Brock Kirwan

摘要

Research suggests that emerging adults with type 1 diabetes demonstrate many neural differences from their peers, including poorer executive functioning. However, limited research has examined whether these differences are associated with alterations in neural activation and whether brain processes vary depending on illness management (i.e., hemoglobin A1c). Using functional magnetic resonance imaging, we examined whether emerging adults with type 1 diabetes showed differences in in executive functioning-related neural activation compared to age-matched peers without type 1 diabetes. We found that, although participants with type 1 diabetes demonstrated similar behavioral inhibition performance to their peers, they showed comparatively greater activation in several interconnected executive functioning-related brain regions, including the left frontal, temporal, and insular regions. We did not find an association between hemoglobin HbA1c and executive function-related neural activation. These findings suggests that individuals with type 1 diabetes likely exert greater neural “effort” in executive functioning-related brain regions to achieve similar levels of inhibitory control when compared to peers without type 1 diabetes.