<p>Nowadays, dissimilar welding can be used to balance the mechanical performance and corrosion resistance of components that operate in harsh environments. This study investigates how pulsed gas metal arc welding influences the microstructure and the pitting corrosion behavior of a dissimilar joint of Inconel 625 superalloy and AL-6XN super austenitic stainless steel. Optical images revealed inhomogeneities, i.e., microsegregation, peninsula-type formation near the AL-6XN/weld metal interface, and banding extending close to the weld metal/IN625 interface. High-magnification images show that carbides, nitrides, carbonitrides, and Laves phase extend dispersedly along the weld metal and base metals interfaces, where 80% of these precipitates exhibited mean sizes between 1 and 2 μm². The Inconel 625/weld metal interface showed the formation of a partially melted zone with a compositional elemental gradient. The solidification growth mode of the weld metal resulted in a mixed microstructure composed of cellular, equiaxed, and columnar dendritic growths. Polarization tests exhibit that the pitting corrosion resistance (Δ<i>E</i>) is mainly influenced by precipitation, the partitioning coefficient, and the presence of inhomogeneities. Both weld interfaces show a negligible Δ<i>E</i> difference. However, Inconel 625 and its heat-affected zone (HAZ) showed lower Δ<i>E</i> than the AL-6XN and its HAZ. Furthermore, potentiostatic polarization shows that as time progresses, the passive film of Inconel 625 and its HAZ becomes more compact and resistant (slope <i>k → </i>− 1) than that of the AL-6XN.</p>