<p>A series of problems, such as instability and sandwich shear failure, can quickly occur on brazed honeycomb aluminum panel, leading to difficulty during its processing and forming. Therefore, to obtain the best process parameters under different conditions, a combination of finite element simulation and experiment to study the compression performance of honeycomb aluminum panels at room temperature and high temperature was used in this project, which provides an effective technical way for compression of honeycomb aluminum panels. It was found that the outer stress of the honeycomb aluminum panel was more significant than the inner stress during flat pressing, and the strain value at the height of 1/3 after compression was about four times that of other positions. Through the flat compression experiment under different strain rates, it was found that with the decrease in strain rate, the maximum compressive stress that can be withheld increases, and the corresponding compression amount decreases. By studying the stress distribution on the flat side pressure at different temperatures, it was found that the rise in temperature leads to a more uniform stress distribution, which affects the final deformation.</p>