Scholarlink

<p>The introduction of molecular markers has significantly improved the prognosis and treatment of endometrial cancer in recent years. As endometrial cancer is usually diagnosed in early stages, surgery is the most important therapeutic aspect and comprises hysterectomy with bilateral adnexectomy. In case of additional risk factors, sentinel node biopsy is recommended. For advanced stages, systematic pelvic and paraaortic lymphadenectomy should also be performed. After surgery, adjuvant therapy should be considered, particularly for patients at a&#xa0;high risk of recurrence. This may include adjuvant radio- and/or systemic therapy, with immunotherapy emerging as a&#xa0;key component of the treatment regimen. In cases of recurrence, endocrine therapy may also be an option. Overall, the treatment of endometrial cancer has become increasingly complex and should be managed in an interdisciplinary approach at a&#xa0;certified gynecologic cancer center.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Endometriumkarzinom – was gibt es Neues?

  • 期刊论文

  • 发表日期：

    2025年2月10日

查看全文
  • Laura Weydandt,
  • Lars-Christian Horn,
  • Katrin Hering,
  • Bahriye Aktas,
  • Nadja Dornhöfer

摘要

The introduction of molecular markers has significantly improved the prognosis and treatment of endometrial cancer in recent years. As endometrial cancer is usually diagnosed in early stages, surgery is the most important therapeutic aspect and comprises hysterectomy with bilateral adnexectomy. In case of additional risk factors, sentinel node biopsy is recommended. For advanced stages, systematic pelvic and paraaortic lymphadenectomy should also be performed. After surgery, adjuvant therapy should be considered, particularly for patients at a high risk of recurrence. This may include adjuvant radio- and/or systemic therapy, with immunotherapy emerging as a key component of the treatment regimen. In cases of recurrence, endocrine therapy may also be an option. Overall, the treatment of endometrial cancer has become increasingly complex and should be managed in an interdisciplinary approach at a certified gynecologic cancer center.