<p>Onconephrology is the study of acute and chronic kidney disease in the context of oncological diseases and their therapy. Acute kidney injury and chronic kidney disease can occur as a&#xa0;result of drug therapy, surgery or radiation therapy, or secondarily in the context of the underlying oncological disease. The accurate assessment of glomerular filtration rate prior to the administration of conventional chemotherapy reduces the risk of both over- and underdosing. Knowledge of the potential renal side effects of conventional chemotherapy, targeted therapies, and immunotherapies allows nephrological recommendations regarding their prevention and monitoring. Treatment of cancer in patients on dialysis and after kidney transplantation is challenging. Given the increased risk for malignancies after kidney transplantation, a&#xa0;sufficient waiting period has to be defined for kidney transplant candidates with a&#xa0;history of cancer.</p>

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Onkonephrologie

  • Julia Seelemann,
  • Eva Schrezenmeier,
  • Sandra Herrmann,
  • Mareike Frick,
  • Kai-Uwe Eckardt

摘要

Onconephrology is the study of acute and chronic kidney disease in the context of oncological diseases and their therapy. Acute kidney injury and chronic kidney disease can occur as a result of drug therapy, surgery or radiation therapy, or secondarily in the context of the underlying oncological disease. The accurate assessment of glomerular filtration rate prior to the administration of conventional chemotherapy reduces the risk of both over- and underdosing. Knowledge of the potential renal side effects of conventional chemotherapy, targeted therapies, and immunotherapies allows nephrological recommendations regarding their prevention and monitoring. Treatment of cancer in patients on dialysis and after kidney transplantation is challenging. Given the increased risk for malignancies after kidney transplantation, a sufficient waiting period has to be defined for kidney transplant candidates with a history of cancer.