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Objective <p>The 3‑year intervention study had the following objectives: (1)&#xa0;to evaluate changes in the cardinal symptoms of fatigue and sensorimotor instability, (2)&#xa0;to improve physical health, (3)&#xa0;to promote and improve mental health, and (4)&#xa0;to promote the quality of life as such and the participation in working life and society.</p> Methodology <p>407 vaccinated nucleocapsid-positive patients were treated at the Lausitz Post-COVID-19 Center (Senftenberg, Germany). Seventy-eight&#xa0;patients with the cardinal syndroms of fatigue and sensorimotor instability fully participated in the intervention study. The evaluation is based on the analysis of the treatment schedule, on individual post-COVID-19 syndromes, and on motor fatigue parameters. Secondary psychosomatic syndromes in 19 patients were treated with intensified cognitive behavioral therapy (CBT).</p> Results <p>In <i>N</i> = 78 patients, the post-COVID-19 core symptoms of fatigue, sensorimotor instability, neuropsychiatric symptoms, cardiac/autonomic dysfunction, and pain improved (goal&#xa0;1). A&#xa0;therapeutic effect was observed for all motor fatigue parameters based on the Cohen’s d&#xa0;value (goal&#xa0;2). Subsequent intensification of CBT with <i>N</i> = 19 (24%) achieved positive effects by increasing patient self-activity and improving self-control (goal&#xa0;3). The results of the standardized questionnaires (<i>N</i> = 26) continue to indicate limitations in participation, quality of life, and mental health (goal&#xa0;4).</p> Conclusion <p>Improvements were observed in post-COVID-19 core symptoms and motor fatigue parameters. Developing secondary psychosomatic symptoms could be reduced with intensified CBT, and participation, quality of life, and mental health were improved.</p>

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Sektorenübergreifendes beanspruchungsgesteuertes Blended-Therapy-Konzept für Post-COVID-19-Patienten

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年6月24日

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  • Thomas Urban,
  • Peter Lohse,
  • Stefan G. Spitzer,
  • Fritjof Reinhardt

摘要

Objective

The 3‑year intervention study had the following objectives: (1) to evaluate changes in the cardinal symptoms of fatigue and sensorimotor instability, (2) to improve physical health, (3) to promote and improve mental health, and (4) to promote the quality of life as such and the participation in working life and society.

Methodology

407 vaccinated nucleocapsid-positive patients were treated at the Lausitz Post-COVID-19 Center (Senftenberg, Germany). Seventy-eight patients with the cardinal syndroms of fatigue and sensorimotor instability fully participated in the intervention study. The evaluation is based on the analysis of the treatment schedule, on individual post-COVID-19 syndromes, and on motor fatigue parameters. Secondary psychosomatic syndromes in 19 patients were treated with intensified cognitive behavioral therapy (CBT).

Results

In N = 78 patients, the post-COVID-19 core symptoms of fatigue, sensorimotor instability, neuropsychiatric symptoms, cardiac/autonomic dysfunction, and pain improved (goal 1). A therapeutic effect was observed for all motor fatigue parameters based on the Cohen’s d value (goal 2). Subsequent intensification of CBT with N = 19 (24%) achieved positive effects by increasing patient self-activity and improving self-control (goal 3). The results of the standardized questionnaires (N = 26) continue to indicate limitations in participation, quality of life, and mental health (goal 4).

Conclusion

Improvements were observed in post-COVID-19 core symptoms and motor fatigue parameters. Developing secondary psychosomatic symptoms could be reduced with intensified CBT, and participation, quality of life, and mental health were improved.