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<p>It is assumed that there is a high number of unreported cases of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Some of these undiagnosed patients suspect that they are suffering from ME/CFS. The aim of this study was to determine whether and, if so, in what respects patients with and without a medical diagnosis of ME/CFS differ.</p><p>For this purpose, the answers of 736 adult ME/CFS patients diagnosed by a doctor (DS1) were compared with those of 189 adult patients without a medical ME/CFS diagnosis (DS2). Sampling was carried out by self-activation/snowball principle. After a descriptive presentation of the results, potential relationships between the various variables were examined (Pearson χ² test/Fisher’s exact test, Levene test, t-test).</p><p>Both groups do not differ significantly in terms of age and gender. However, DS2 patients used fewer medical/alternative medicine services. They reported fewer symptoms, but did not differ in terms of their range of symptoms. In contrast to the DS1 group, the number of symptoms in the DS2 group does not decrease with age, nor is there a gender difference. Unlike studies that compare the frequency of symptoms in ME/CFS patients with patients who do not meet the Canadian consensus criteria (CCC), the difference between our two groups is significantly smaller.</p><p>This leads to the hypothesis that at least some of our undiagnosed participants meet the CCC. Confirmation of this hypothesis could lead to earlier diagnosis in this patient group in the future, so that measures can be taken earlier that can positively influence the course of the disease.</p>

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Erkrankte mit ärztlich diagnostizierter Myalgischer Enzephalomyelitis/chronischem Fatigue-Syndrom (ME/CFS-) im Vergleich zu Erkrankten, die vermuten an ME/CFS zu leiden

  • 期刊论文

  • 发表日期：

    2025年3月5日

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  • Lotte Habermann-Horstmeier,
  • Lukas M. Horstmeier

摘要

It is assumed that there is a high number of unreported cases of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Some of these undiagnosed patients suspect that they are suffering from ME/CFS. The aim of this study was to determine whether and, if so, in what respects patients with and without a medical diagnosis of ME/CFS differ.

For this purpose, the answers of 736 adult ME/CFS patients diagnosed by a doctor (DS1) were compared with those of 189 adult patients without a medical ME/CFS diagnosis (DS2). Sampling was carried out by self-activation/snowball principle. After a descriptive presentation of the results, potential relationships between the various variables were examined (Pearson χ² test/Fisher’s exact test, Levene test, t-test).

Both groups do not differ significantly in terms of age and gender. However, DS2 patients used fewer medical/alternative medicine services. They reported fewer symptoms, but did not differ in terms of their range of symptoms. In contrast to the DS1 group, the number of symptoms in the DS2 group does not decrease with age, nor is there a gender difference. Unlike studies that compare the frequency of symptoms in ME/CFS patients with patients who do not meet the Canadian consensus criteria (CCC), the difference between our two groups is significantly smaller.

This leads to the hypothesis that at least some of our undiagnosed participants meet the CCC. Confirmation of this hypothesis could lead to earlier diagnosis in this patient group in the future, so that measures can be taken earlier that can positively influence the course of the disease.