<p>The healthcare institutions have started inculcating practices towards personalized care to its patients. Genomic data has now become an inevitable component of healthcare data allowing realization of personalize care of the patients. Medical practitioners are utilizing different technologies for efficient clinical interpretations of genomic data. The genomic data poses many challenges related to its management, amongst which data size and sensitivity are critical. The blockchain technology, a recent and still evolving technology, provides a single integrated solution for the various challenges encountered in managing healthcare data, both genomic and non-genomic. But still there are many challenges yet to be resolved in the domain of genomics and connected technological solutions. This paper presents a systematic literature review covering the research done on genomic data management using blockchain technology in healthcare. The review has incorporated 44 research and 43 review papers. We have designed our study based on 4 research questions targeted to cover efforts on genomic data management via blockchain technology. To our knowledge, majority of the research has focused on data sharing, privacy and security of genomic data. This systematic literature review (SLR) will contribute in identifying research gaps and directions for untouched areas.</p> Graphical Abstract <p></p>