Scholarlink

<p>Percutaneous transluminal angioplasty with stenting is extensively applied for treatment of atherosclerosis. However, the effects of dogboning (<i>d</i><sub><i>b</i></sub>), foreshortening (<i>f</i><sub><i>s</i></sub>), longitudinal recoil (<i>l</i><sub><i>r</i></sub>) and radial recoil (<i>R</i><sub><i>r</i></sub>) usually occur to inflict damage to the artery and make the positioning difficult during the cardiovascular stent (CS) expansion to the maximum and after the inflated balloon removing. In the article, the design and manufacture of a CS were carried out based on digital twin (DT) technology rather than traditional expertise- and experience-based methods. The highly kinetic model of a CS was firstly derived from its upfront proposed geometric configuration, governing equations of solid mechanics and boundary conditions to construct its DT through virtual reality (VR). Then global sensitivity analysis (GSA) and dynamic response optimization (DRO) was implemented to optimize the material and processing parameters including Young's modulus (<i>E</i>), isotropic tangent modulus (<i>E</i><sub><i>t</i></sub>), Poisson's ratio (<i>ν</i>), density (<i>ρ</i>) and initial yield stress (<i>σ</i>), in order to obtain a satisfied behavior requirements for effects of <i>d</i><sub><i>b</i></sub><i>, f</i><sub><i>s</i></sub><i>, l</i><sub><i>r</i></sub> and<i> R</i><sub><i>r</i></sub>. The prototype experiment result showed that the CS made of shape memory Nitinol with optimal material and processing parameters (<i>ρ</i> = 7050&#xa0;kg&#xa0;m<sup>−3</sup>, <i>ν</i> = 0.27,<i> E</i> = 205 GPa,<i> E</i><sub><i>t</i></sub> = 675.13&#xa0;MPa and <i>σ</i> = 198.49&#xa0;MPa) obtained from its digital twin through VR simulation could have desired behavior performance characteristics, such as weak effect of <i>d</i><sub><i>b</i></sub> and <i>f</i><sub><i>s</i></sub> during the CS expansion to the maximum, and <i>l</i><sub><i>r</i></sub> (-0.9%), distal <i>R</i><sub><i>r</i></sub> (0.4%) and central <i>R</i><sub><i>r</i></sub> (0.7%) after the inflated balloon removing.</p> Graphical abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Digital twin-enabled cardiovascular stent optimization: a virtual reality-driven approach to mitigate angioplasty-related deformations

  • 期刊论文

  • 发表日期：

    2025年3月26日

查看全文
  • Juanyi Wang,
  • Yi Zhang,
  • Yang Yang,
  • Xiao Wen,
  • Xiaodong Xing,
  • Zhiyong Zhang,
  • Chen Dong

摘要

Percutaneous transluminal angioplasty with stenting is extensively applied for treatment of atherosclerosis. However, the effects of dogboning (db), foreshortening (fs), longitudinal recoil (lr) and radial recoil (Rr) usually occur to inflict damage to the artery and make the positioning difficult during the cardiovascular stent (CS) expansion to the maximum and after the inflated balloon removing. In the article, the design and manufacture of a CS were carried out based on digital twin (DT) technology rather than traditional expertise- and experience-based methods. The highly kinetic model of a CS was firstly derived from its upfront proposed geometric configuration, governing equations of solid mechanics and boundary conditions to construct its DT through virtual reality (VR). Then global sensitivity analysis (GSA) and dynamic response optimization (DRO) was implemented to optimize the material and processing parameters including Young's modulus (E), isotropic tangent modulus (Et), Poisson's ratio (ν), density (ρ) and initial yield stress (σ), in order to obtain a satisfied behavior requirements for effects of db, fs, lr and Rr. The prototype experiment result showed that the CS made of shape memory Nitinol with optimal material and processing parameters (ρ = 7050 kg m−3, ν = 0.27, E = 205 GPa, Et = 675.13 MPa and σ = 198.49 MPa) obtained from its digital twin through VR simulation could have desired behavior performance characteristics, such as weak effect of db and fs during the CS expansion to the maximum, and lr (-0.9%), distal Rr (0.4%) and central Rr (0.7%) after the inflated balloon removing.

Graphical abstract