<p>Dynamics model for polysaccharide (HNCVP) extraction process from <i>Nostoc commune</i> Vauch was established. The process was fitted with the second Fick’s law, and exhibited a spontaneous and exothermic process. A maximal HNCVP yield was obtained under temperature of 363.15 K, extraction time of 150 min and solid-liquid ratio of 1:50&#xa0;g/mL. The apparent viscosity of HNCVP affected significantly by pH and the type and intensity of ions, and increased significantly with the increase of Na<sup>+</sup> and K<sup>+</sup> concentration, while significant decreased after the addition of Ca<sup>2+</sup> and Zn<sup>2+</sup>. In addition, HNCVP can inhibit the proliferation of Bovine Viral Diarrhea Virus (BVDV) by interference with 5’ UTR gene synthesis, and protection cells growth by regulating the relatively expression of IRF<i>-1</i> and <i>IRF-3</i> in Madin-Darby bovine kidney cells, where interferon maybe activated for virus elimination and defense. These results presented the potential of HNCVP as a functional additive in the food and pharmaceutical industries.</p>

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Extraction Kinetics, Thermodynamics, Biological Characteristics of Polysaccharide From Nostoc Commune Vauch by Hot Water Assisted Extraction

  • Guangrui Yang,
  • Chunyuan Zhang,
  • Haining He,
  • Lihong Li,
  • Xia Hong,
  • Yonggang Wang

摘要

Dynamics model for polysaccharide (HNCVP) extraction process from Nostoc commune Vauch was established. The process was fitted with the second Fick’s law, and exhibited a spontaneous and exothermic process. A maximal HNCVP yield was obtained under temperature of 363.15 K, extraction time of 150 min and solid-liquid ratio of 1:50 g/mL. The apparent viscosity of HNCVP affected significantly by pH and the type and intensity of ions, and increased significantly with the increase of Na+ and K+ concentration, while significant decreased after the addition of Ca2+ and Zn2+. In addition, HNCVP can inhibit the proliferation of Bovine Viral Diarrhea Virus (BVDV) by interference with 5’ UTR gene synthesis, and protection cells growth by regulating the relatively expression of IRF-1 and IRF-3 in Madin-Darby bovine kidney cells, where interferon maybe activated for virus elimination and defense. These results presented the potential of HNCVP as a functional additive in the food and pharmaceutical industries.