<p>We investigate the population dynamics and Casimir-Polder (CP) force experienced by an atom placed near a two-dimensional anisotropic surface (TDAS) supporting surface plasmon polaritons (SPPs). Within the non-Markovian macroscopic quantum electrodynamics framework, we first analyze how atom-SPP coupling influences the evolution of the atomic population and the temporal behavior of the CP force. Our results show that variations in the atomic dipole moment, atom-surface distance, transition frequency, and carrier concentration can selectively modulate the coupling strength between the atom and the SPP modes. In the strong coupling regime, the system shows oscillatory behavior in both the population and CP force dynamics, with an enhanced force amplitude and periodic directional changes. By contrast, in the weak coupling regime, the dynamics are dominated by exponential decay. Additionally, when a coherent driving field is introduced, we adopt the Markovian approximation and demonstrate that the system can reach a steady state with a finite excited-state population, resulting in a persistent CP force that is highly sensitive to the driving frequency and strength. These findings indicate that dispersion forces can be precisely tailored through the combined influence of anisotropic plasmonic platforms and external coherent driving, which paves the way for new opportunities in nanoscale atomic control and manipulation within plasmonic systems.</p>