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<p>This study presents a novel dual-band metamaterial sensor designed for the detection of cancer cells. The proposed sensor features a gold octagonal loop structure with carefully constructed gaps, achieving perfect absorption at&#xa0;1994 GHz&#xa0;and&#xa0;2700 GHz&#xa0;with absorption of&#xa0;100%&#xa0;and&#xa0;88%, respectively. The sensor demonstrates exceptional sensitivity to the analyte refractive index (RI) change, with sensitivities of&#xa0;600&#xa0;GHz/RIU&#xa0;and&#xa0;800&#xa0;GHz/RIU&#xa0;for the first and second resonance bands, respectively, with corresponding quality factor of 12.24 and 8.9 and a FOM of 3.66 and 2.64, respectively. Additionally, the reported design can be used for sensing different types of cancer types such as breast, cervical, Jurkat, PC12, and MCF-7 with an average sensitivity of&#xa0;560 GHz/RIU&#xa0;and&#xa0;770 GHz/RIU&#xa0;for the first and second resonances, respectively. The design is also simple and can be fabricated by current technology using photolithography technique. These results surpass those reported in recent literature, highlighting the sensor’s superior performance. Additionally, the sensor performance exhibits high linearity across the studied frequency range, robustness against fabrication tolerances, and compatibility with established fabrication technologies. The proposed metamaterial sensor represents a significant advancement in cancer detection, offering high sensitivity, flexibility, and ease of integration into biomedical applications.</p>

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Design of Highly Sensitive Dual-Band THz Metamaterial Sensor for Cancer Early Detection

  • 期刊论文

  • 发表日期：

    2025年7月12日

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  • Hoda M. Mamoun,
  • Mohamed Farhat O. Hameed,
  • O. Hatem,
  • S. T. Assar,
  • S. S. A. Obayya,
  • Mohammad Y. Azab

摘要

This study presents a novel dual-band metamaterial sensor designed for the detection of cancer cells. The proposed sensor features a gold octagonal loop structure with carefully constructed gaps, achieving perfect absorption at 1994 GHz and 2700 GHz with absorption of 100% and 88%, respectively. The sensor demonstrates exceptional sensitivity to the analyte refractive index (RI) change, with sensitivities of 600 GHz/RIU and 800 GHz/RIU for the first and second resonance bands, respectively, with corresponding quality factor of 12.24 and 8.9 and a FOM of 3.66 and 2.64, respectively. Additionally, the reported design can be used for sensing different types of cancer types such as breast, cervical, Jurkat, PC12, and MCF-7 with an average sensitivity of 560 GHz/RIU and 770 GHz/RIU for the first and second resonances, respectively. The design is also simple and can be fabricated by current technology using photolithography technique. These results surpass those reported in recent literature, highlighting the sensor’s superior performance. Additionally, the sensor performance exhibits high linearity across the studied frequency range, robustness against fabrication tolerances, and compatibility with established fabrication technologies. The proposed metamaterial sensor represents a significant advancement in cancer detection, offering high sensitivity, flexibility, and ease of integration into biomedical applications.