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<p>In this study, we propose a symmetric, polished D-shaped photonic crystal fiber (PCF) biosensor based on surface plasmon resonance (SPR). Symmetrical elliptical notches are fabricated on the dual-sided polished D-shaped surfaces, and a gold film is coated via atomic layer deposition (ALD) to enhance the SPR effect. Numerical simulations employing the finite element method (FEM) demonstrate that the sensor can achieve a broad refractive index (RI) detection range of 1.30 to 1.40. The maximum wavelength sensitivity (WS) is 51,800 nm/RIU, and the maximum resolution is 1.93 × 10<sup>−6</sup> RIU. The sensor exhibits a linear response within RI 1.35–1.39, achieving wavelength sensitivities of 15,714.29 nm/RIU and 10,950 nm/RIU for detecting blood cancer and monitoring skin cancer, respectively. The proposed PCF-SPR sensor exhibits structural simplicity and ease of fabrication, along with high sensitivity and a broad detection range. These combined advantages not only enhance its potential for cancer cell detection but also enable diverse applications in fields such as biosensing, environmental monitoring, and food safety.</p>

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High Sensitivity Surface Plasmon Resonance Biosensor Using Double-Notches Photonic Crystal Fiber

  • 期刊论文

  • 发表日期：

    2025年6月12日

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  • Yukun Zhu,
  • Honggang Pan,
  • Yi Zhou,
  • Qingcheng You,
  • Licui Ji,
  • Yichen Li,
  • Bin Li,
  • Xu Gao,
  • Xing Wang

摘要

In this study, we propose a symmetric, polished D-shaped photonic crystal fiber (PCF) biosensor based on surface plasmon resonance (SPR). Symmetrical elliptical notches are fabricated on the dual-sided polished D-shaped surfaces, and a gold film is coated via atomic layer deposition (ALD) to enhance the SPR effect. Numerical simulations employing the finite element method (FEM) demonstrate that the sensor can achieve a broad refractive index (RI) detection range of 1.30 to 1.40. The maximum wavelength sensitivity (WS) is 51,800 nm/RIU, and the maximum resolution is 1.93 × 10−6 RIU. The sensor exhibits a linear response within RI 1.35–1.39, achieving wavelength sensitivities of 15,714.29 nm/RIU and 10,950 nm/RIU for detecting blood cancer and monitoring skin cancer, respectively. The proposed PCF-SPR sensor exhibits structural simplicity and ease of fabrication, along with high sensitivity and a broad detection range. These combined advantages not only enhance its potential for cancer cell detection but also enable diverse applications in fields such as biosensing, environmental monitoring, and food safety.