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<p>Early detection of skin cancer is essential to reduce fatalities, as it allows for timely treatment, improves survival rates, and enables less invasive procedures, leading to better long-term outcomes. We have proposed a biosensor design utilizing graphene material to efficiently diagnose skin cancer at an early stage, enabling quicker detection. The sensor features an Au-SiO2-Au layer design, enhancing efficiency and performance in detecting skin cancer. This design achieves a remarkable sensitivity of 1300&#xa0;nm/RIU, optimizing the sensor's performance and enabling precise detection of skin cancer at an early stage with enhanced accuracy and reliability. The optimization of structural parameters is applied to enhance the sensor’s efficiency, improving its performance in detecting cancer efficiently. This adjustment ensures greater accuracy, sensitivity, and reliability in the biosensor’s overall functionality. Both E-field and H-field analyses are presented, providing a comprehensive understanding of the sensor’s electromagnetic behaviour and performance. The efficient sensor is an excellent choice for biomedical applications, particularly in skin cancer detection, offering high sensitivity, accuracy, and reliability for early diagnosis and improved patient outcomes.</p>

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Advanced Graphene-Integrated Surface Plasmon Resonance Biosensor for Precise Skin Cancer Detection Using Au-SiO2-Au Nanostructured Materials and Enhanced Sensitivity

  • 期刊论文

  • 发表日期：

    2025年4月14日

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  • Anushkannan N K,
  • Lakshmi R,
  • Vijayakumar K,
  • Fahad Ahmed Al-Zahrani

摘要

Early detection of skin cancer is essential to reduce fatalities, as it allows for timely treatment, improves survival rates, and enables less invasive procedures, leading to better long-term outcomes. We have proposed a biosensor design utilizing graphene material to efficiently diagnose skin cancer at an early stage, enabling quicker detection. The sensor features an Au-SiO2-Au layer design, enhancing efficiency and performance in detecting skin cancer. This design achieves a remarkable sensitivity of 1300 nm/RIU, optimizing the sensor's performance and enabling precise detection of skin cancer at an early stage with enhanced accuracy and reliability. The optimization of structural parameters is applied to enhance the sensor’s efficiency, improving its performance in detecting cancer efficiently. This adjustment ensures greater accuracy, sensitivity, and reliability in the biosensor’s overall functionality. Both E-field and H-field analyses are presented, providing a comprehensive understanding of the sensor’s electromagnetic behaviour and performance. The efficient sensor is an excellent choice for biomedical applications, particularly in skin cancer detection, offering high sensitivity, accuracy, and reliability for early diagnosis and improved patient outcomes.