Scholarlink

<p>This research unveils a pioneering circular–shaped photonic crystal fiber–based surface plasmon resonance biosensor, utilizing gold to detect a variety of cancerous cells, including MDA-MB-231, HeLa, MCF-7, Jurkat, and PC12. The sensor’s design and modeling were conducted using the full-vector finite element method (FEM) in COMSOL Multiphysics v6.2, ensuring high precision and reliability. Gold was chosen as the plasmonic material due to its excellent chemical stability, biocompatibility, and strong plasmonic resonance properties. These characteristics make gold an ideal candidate for enhancing the sensitivity and specificity of biosensors. The innovative design of the PCF structure enhances the interaction between the light and the analyte, improving the sensor’s overall performance. The biosensor demonstrates exceptional performance, exhibiting higher sensitivity and better resolution compared to existing methods. It achieves a MaxWS of 17,857 nm/RIU and a MaxAS of 1863 RIU<sup>−1</sup>. These impressive results indicate the sensor’s superior precision and responsiveness in detecting cancerous cells. This innovative biosensor presents significant potential in revolutionizing cancer diagnostics by enabling earlier and more accurate identification of cancerous cells. Its high sensitivity and specificity could greatly enhance diagnostic precision and improve patient outcomes, marking a substantial advancement in the field of medical diagnostics. The combination of advanced modeling techniques and the use of gold as a plasmonic material has enabled the development of a highly effective diagnostic tool with broad applications in medical research and clinical practice.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Ultra-Sensitive Au-based Circular Photonic Fibers Based Surface Plasmonic Resonance Biosensor for Various Cancer Level Diagnostics and Detection

  • 期刊论文

  • 发表日期：

    2025年4月8日

查看全文
  • Md Abu Huraiya,
  • Momen Sahriar Shoshi,
  • Kisalaya Chakrabarti,
  • Hitoshi Tabata,
  • Sankar Ganesh Ramaraj,
  • S. M. Abdur Razzak,
  • Mahmoud M. A. Eid,
  • Ahmed Nabih Zaki Rashed

摘要

This research unveils a pioneering circular–shaped photonic crystal fiber–based surface plasmon resonance biosensor, utilizing gold to detect a variety of cancerous cells, including MDA-MB-231, HeLa, MCF-7, Jurkat, and PC12. The sensor’s design and modeling were conducted using the full-vector finite element method (FEM) in COMSOL Multiphysics v6.2, ensuring high precision and reliability. Gold was chosen as the plasmonic material due to its excellent chemical stability, biocompatibility, and strong plasmonic resonance properties. These characteristics make gold an ideal candidate for enhancing the sensitivity and specificity of biosensors. The innovative design of the PCF structure enhances the interaction between the light and the analyte, improving the sensor’s overall performance. The biosensor demonstrates exceptional performance, exhibiting higher sensitivity and better resolution compared to existing methods. It achieves a MaxWS of 17,857 nm/RIU and a MaxAS of 1863 RIU−1. These impressive results indicate the sensor’s superior precision and responsiveness in detecting cancerous cells. This innovative biosensor presents significant potential in revolutionizing cancer diagnostics by enabling earlier and more accurate identification of cancerous cells. Its high sensitivity and specificity could greatly enhance diagnostic precision and improve patient outcomes, marking a substantial advancement in the field of medical diagnostics. The combination of advanced modeling techniques and the use of gold as a plasmonic material has enabled the development of a highly effective diagnostic tool with broad applications in medical research and clinical practice.